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Lars M T Eijssen

Explore the profile of Lars M T Eijssen including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 822
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Recent Articles
1.
Bahram Sangani N, Koetsier J, Gomes A, Diogo M, Fernandes T, Bouwman F, et al.
Cell Mol Life Sci . 2024 Sep; 81(1):410. PMID: 39305343
Rett syndrome (RTT) is a neurodevelopmental disorder caused by de novo mutations in the MECP2 gene. Although miRNAs in extracellular vesicles (EVs) have been suggested to play an essential role...
2.
Koetsier J, Cavill R, Reijnders R, Harvey J, Homann J, Kouhsar M, et al.
Alzheimers Dement . 2024 Aug; 20(10):6682-6698. PMID: 39193899
Introduction: The established link between DNA methylation and pathophysiology of dementia, along with its potential role as a molecular mediator of lifestyle and environmental influences, positions blood-derived DNA methylation as...
3.
Bahram Sangani N, Koetsier J, Melius J, Kutmon M, Ehrhart F, Evelo C, et al.
Sci Rep . 2024 Jun; 14(1):14666. PMID: 38918466
Due to its involvement in physiological and pathological processes, histone deacetylase 6 (HDAC6) is considered a promising pharmaceutical target for several neurological manifestations. However, the exact regulatory role of HDAC6...
4.
Ahmed Z, Zain Al-Abeden M, Al Abdin M, Muqresh M, Al Jowf G, Eijssen L, et al.
Stem Cell Res Ther . 2024 Jun; 15(1):165. PMID: 38867306
Background: Mesenchymal stem cells (MSCs) have emerged as living biodrugs for myocardial repair and regeneration. Recent randomized controlled trials (RCTs) have reported that MSC-based therapy is safe and effective in...
5.
Al Jowf G, Ahmed Z, Reijnders R, de Nijs L, Eijssen L
Int J Mol Sci . 2023 Mar; 24(6). PMID: 36982313
Post-traumatic stress disorder (PTSD) can become a chronic and severely disabling condition resulting in a reduced quality of life and increased economic burden. The disorder is directly related to exposure...
6.
Van der Zee Y, Eijssen L, Mews P, Ramakrishnan A, Alvarez K, Lardner C, et al.
Mol Psychiatry . 2022 Jul; 27(11):4536-4549. PMID: 35902629
Major depressive disorder (MDD) is the leading cause of disability worldwide. There is an urgent need for objective biomarkers to diagnose this highly heterogeneous syndrome, assign treatment, and evaluate treatment...
7.
Al Jowf G, Ahmed Z, An N, Reijnders R, Ambrosino E, Rutten B, et al.
Int J Environ Res Public Health . 2022 Jun; 19(11). PMID: 35682057
Trauma exposure is one of the most important and prevalent risk factors for mental and physical ill-health. Prolonged or excessive stress exposure increases the risk of a wide variety of...
8.
Liesenborghs I, Schouten J, Kutmon M, Gorgels T, Evelo C, Hubens W, et al.
Genomics . 2022 Feb; 114(2):110280. PMID: 35124177
Purpose: The trabecular meshwork (TM) is situated in the most frontal part of the eye and is thought to play an important role in the regulation of the eye pressure....
9.
Al Jowf G, Snijders C, Rutten B, de Nijs L, Eijssen L
Int J Mol Sci . 2021 Oct; 22(19). PMID: 34639084
Exposure to trauma is one of the most important and prevalent risk factors for mental and physical ill-health. Excessive or prolonged stress exposure increases the risk of a wide variety...
10.
Van der Zee Y, Lardner C, Parise E, Mews P, Ramakrishnan A, Patel V, et al.
Biol Psychiatry . 2021 Apr; 91(1):81-91. PMID: 33896623
Background: Major depressive disorder is a pervasive and debilitating syndrome characterized by mood disturbances, anhedonia, and alterations in cognition. While the prevalence of major depressive disorder is twice as high...