Michele C Buck
Overview
Explore the profile of Michele C Buck including associated specialties, affiliations and a list of published articles.
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10
Citations
114
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Recent Articles
1.
Buck M, Bast L, Hecker J, Riviere J, Rothenberg-Thurley M, Vogel L, et al.
iScience
. 2023 Jul;
26(8):107328.
PMID: 37520699
Clonal hematopoiesis of indeterminate potential (CHIP) describes the age-related acquisition of somatic mutations in hematopoietic stem/progenitor cells (HSPC) leading to clonal blood cell expansion. Although CHIP mutations drive myeloid malignancies...
2.
Riviere J, Hock J, Buck M, Hecker J, Gotze K, van der Garde M
Stem Cell Res Ther
. 2023 Mar;
14(1):36.
PMID: 36882822
Bone marrow samples from discarded femoral heads are often used as healthy controls in studies investigating the in vitro characteristics of cells from patients with hematologic malignancies. Since patient samples...
3.
Lang J, Buck M, Riviere J, Stambouli O, Sachenbacher K, Choudhary P, et al.
Front Oncol
. 2022 Oct;
12:949261.
PMID: 36263223
Cellular crosstalk between hematopoietic stem/progenitor cells and the bone marrow (BM) niche is vital for the development and maintenance of myeloid malignancies. These compartments can communicate bidirectional transfer of extracellular...
4.
Hartmann L, Hecker J, Rothenberg-Thurley M, Riviere J, Jentzsch M, Ksienzyk B, et al.
Leukemia
. 2022 Sep;
36(11):2647-2655.
PMID: 36131041
Clonal hematopoiesis (CH) is characterized by somatic mutations in blood cells of individuals without hematologic disease. While the mutational landscape of CH in peripheral blood (PB) has been well characterized,...
5.
Odinius T, Buschhorn L, Wagner C, Hauch R, Dill V, Dechant M, et al.
J Cancer Res Clin Oncol
. 2021 Oct;
148(2):331-340.
PMID: 34654952
Purpose: Hypereosinophilia represents a heterogenous group of severe medical conditions characterized by elevated numbers of eosinophil granulocytes in peripheral blood, bone marrow or tissue. Treatment options for hypereosinophilia remain limited...
6.
Hecker J, Hartmann L, Riviere J, Buck M, van der Garde M, Rothenberg-Thurley M, et al.
Blood
. 2021 Jun;
138(18):1727-1732.
PMID: 34139005
Clonal hematopoiesis (CH) is an age-related condition predisposing to blood cancer and cardiovascular disease (CVD). Murine models demonstrate CH-mediated altered immune function and proinflammation. Low-grade inflammation has been implicated in...
7.
Tirado-Gonzalez I, Descot A, Soetopo D, Nevmerzhitskaya A, Schaffer A, Kur I, et al.
Cancer Discov
. 2021 Jun;
11(11):2924-2943.
PMID: 34103328
Acute leukemias are systemic malignancies associated with a dire outcome. Because of low immunogenicity, leukemias display a remarkable ability to evade immune control and are often resistant to checkpoint blockade....
8.
Schouten J, Matek C, Jacobs L, Buck M, Bosnacki D, Marr C
Sci Rep
. 2021 Apr;
11(1):7995.
PMID: 33846442
Convolutional neural networks (CNNs) excel as powerful tools for biomedical image classification. It is commonly assumed that training CNNs requires large amounts of annotated data. This is a bottleneck in...
9.
Weickert M, Hecker J, Buck M, Schreck C, Riviere J, Schiemann M, et al.
Sci Rep
. 2021 Mar;
11(1):5944.
PMID: 33723276
Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are clonal hematopoietic stem cell disorders with a poor prognosis, especially for elderly patients. Increasing evidence suggests that alterations in the non-hematopoietic...
10.
Bast L, Buck M, Hecker J, Oostendorp R, Gotze K, Marr C
iScience
. 2021 Mar;
24(2):102120.
PMID: 33665548
Classically, hematopoietic stem cell (HSC) differentiation is assumed to occur via progenitor compartments of decreasing plasticity and increasing maturity in a specific, hierarchical manner. The classical hierarchy has been challenged...