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Carsten Marr

Explore the profile of Carsten Marr including associated specialties, affiliations and a list of published articles. Areas
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Articles 84
Citations 2009
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Recent Articles
1.
Unterauer E, Schentarra E, Jevdokimenko K, Boushehri S, Marr C, Opazo F, et al.
STAR Protoc . 2025 Mar; 6(1):103637. PMID: 40048420
To unravel the complexity of biological processes, it is necessary to resolve the underlying protein organization down to single proteins. Here, we present a protocol for secondary label-based unlimited multiplexed...
2.
Madni H, Umer R, Zottin S, Marr C, Foresti G
Int J Med Inform . 2025 Jan; 195:105806. PMID: 39854783
Background: Segmentation models for clinical data experience severe performance degradation when trained on a single client from one domain and distributed to other clients from different domain. Federated Learning (FL)...
3.
Napoli M, Immler R, Rohwedder I, Lupperger V, Pfabe J, Gonzalez Pisfil M, et al.
Elife . 2024 Dec; 13. PMID: 39699020
S100A8/A9 is an endogenous alarmin secreted by myeloid cells during many acute and chronic inflammatory disorders. Despite increasing evidence of the proinflammatory effects of extracellular S100A8/A9, little is known about...
4.
Schulz M, Bleser S, Groels M, Bosnacki D, Burger J, Chiorazzi N, et al.
iScience . 2024 Dec; 27(12):111242. PMID: 39628582
The Bruton tyrosine kinase inhibitor ibrutinib is an effective treatment for patients with chronic lymphocytic leukemia (CLL). While it rapidly reduces lymph node and spleen size, it initially increases the...
5.
Kuck L, McNamee A, Bordukova M, Sadafi A, Marr C, Peart J, et al.
Proc Natl Acad Sci U S A . 2024 Aug; 121(36):e2407765121. PMID: 39207733
Hematopoietic stem cells surrender organelles during differentiation, leaving mature red blood cells (RBC) devoid of transcriptional machinery and mitochondria. The resultant absence of cellular repair capacity limits RBC circulatory longevity,...
6.
Elfert E, Kaminski W, Matek C, Hoermann G, Axelsen E, Marr C, et al.
Clin Chem Lab Med . 2024 Jun; 62(12):2498-2506. PMID: 38879789
Objectives: Serum protein electrophoresis (SPE) in combination with immunotyping (IMT) is the diagnostic standard for detecting monoclonal proteins (M-proteins). However, interpretation of SPE and IMT is weakly standardized, time consuming...
7.
Caulier B, Joaquina S, Gelebart P, Dowling T, Kaveh F, Thomas M, et al.
Cell Rep Med . 2024 May; 5(6):101572. PMID: 38754420
Acute myeloid leukemia (AML) is characterized by the accumulation of immature myeloid cells in the bone marrow and the peripheral blood. Nearly half of the AML patients relapse after standard...
8.
Unterauer E, Boushehri S, Jevdokimenko K, Masullo L, Ganji M, Sograte-Idrissi S, et al.
Cell . 2024 Mar; 187(7):1785-1800.e16. PMID: 38552614
To understand biological processes, it is necessary to reveal the molecular heterogeneity of cells by gaining access to the location and interaction of all biomolecules. Significant advances were achieved by...
9.
Boushehri S, Kornivetc A, Winter D, Kazeminia S, Essig K, Schmich F, et al.
Cell Rep Methods . 2024 Feb; 4(2):100715. PMID: 38412831
Imaging flow cytometry (IFC) allows rapid acquisition of numerous single-cell images per second, capturing information from multiple fluorescent channels. However, the traditional process of staining cells with fluorescently labeled conjugated...
10.
Frenz-Wiessner S, Fairley S, Buser M, Goek I, Salewskij K, Jonsson G, et al.
Nat Methods . 2024 Feb; 21(5):868-881. PMID: 38374263
The human bone marrow (BM) niche sustains hematopoiesis throughout life. We present a method for generating complex BM-like organoids (BMOs) from human induced pluripotent stem cells (iPSCs). BMOs consist of...