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Michel Simonneau

Explore the profile of Michel Simonneau including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 42
Citations 972
Followers 0
Related Specialties
Genetics
Neurology
Molecular Biology
Top 10 Co-Authors
Aude-Marie Lepagnol-Bestel
Philip Gorwood
Nicolas Ramoz
Jean-Marie Moalic
Yann Loe-Mie
Gilles Maussion
Claude Gaultier
Beatrice Levacher
Virginie Nepote
Fabien Guimiot
Published In
Hum Mol Genet
Pediatr Res
Respir Physiol Neurobiol
Neuroreport
Gene Expr Patterns
Affiliations
Soon will be listed here.
Recent Articles
1.
DYRK1A Up-Regulation Specifically Impairs a Presynaptic Form of Long-Term Potentiation
Lepagnol-Bestel A, Haziza S, Viard J, Salin P, Duchon A, Herault Y, et al.
Life (Basel) . 2025 Feb; 15(2). PMID: 40003558
Chromosome 21 DYRK1A kinase is associated with a variety of neuronal diseases including Down syndrome. However, the functional impact of this kinase at the synapse level remains unclear. We studied...
2.
AUTS2 expression within mammalian lineage: A predictor of neural networks involved in autism spectrum disorders
Lepagnol-Bestel A, Loe-Mie Y, Bensaid M, Simonneau M
Genes Dis . 2025 Feb; 12(3):101440. PMID: 39897131
No abstract available.
3.
Author Correction: BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets
Manubens-Gil L, Zhou Z, Chen H, Ramanathan A, Liu X, Liu Y, et al.
Nat Methods . 2024 Aug; 21(10):1959. PMID: 39090383
No abstract available.
4.
De Novo Variants Found in Three Distinct Schizophrenia Populations Hit a Common Core Gene Network Related to Microtubule and Actin Cytoskeleton Gene Ontology Classes
Loe-Mie Y, Plancon C, Dubertret C, Yoshikawa T, Yalcin B, Collins S, et al.
Life (Basel) . 2024 Feb; 14(2). PMID: 38398753
Schizophrenia (SZ) is a heterogeneous and debilitating psychiatric disorder with a strong genetic component. To elucidate functional networks perturbed in schizophrenia, we analysed a large dataset of whole-genome studies that...
5.
BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets
Manubens-Gil L, Zhou Z, Chen H, Ramanathan A, Liu X, Liu Y, et al.
Nat Methods . 2023 Apr; 20(6):824-835. PMID: 37069271
BigNeuron is an open community bench-testing platform with the goal of setting open standards for accurate and fast automatic neuron tracing. We gathered a diverse set of image volumes across...
6.
Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease
Viard J, Loe-Mie Y, Daudin R, Khelfaoui M, Plancon C, Boland A, et al.
Life Sci Alliance . 2022 Aug; 5(12). PMID: 35914814
Down syndrome (DS) is caused by human chromosome 21 (HSA21) trisomy. It is characterized by a poorly understood intellectual disability (ID). We studied two mouse models of DS, one with...
7.
Impact of α-Synuclein Fibrillar Strains and β-Amyloid Assemblies on Mouse Cortical Neurons Endo-Lysosomal Logistics
Chou Q, Alik A, Marquier F, Melki R, Treussart F, Simonneau M
eNeuro . 2022 Apr; 9(3). PMID: 35470226
Endosomal transport and positioning cooperate in the establishment of neuronal compartment architecture, dynamics, and function, contributing to neuronal intracellular logistics. Furthermore, dysfunction of endo-lysosomal has been identified as a common...
8.
Corrigendum to: DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down syndrome
Lepagnol-Bestel A, Zvara A, Maussion G, Quignon F, Ngimbous B, Ramoz N, et al.
Hum Mol Genet . 2021 Dec; 31(12):2106-2107. PMID: 34918050
No abstract available.
9.
Looking beyond the usual suspects: sulfide stress in schizophrenia pathophysiology
Simonneau M
EMBO Mol Med . 2019 Oct; 11(12):e10983. PMID: 31660695
Schizophrenia is a complex, multifactorial disease that displays heterogeneous behavioral and cognitive syndrome (Lieberman & First, 2018). The origin of schizophrenia appears to lie in genetic and/or environmental disruption of...
10.
HENA, heterogeneous network-based data set for Alzheimer's disease
Sugis E, Dauvillier J, Leontjeva A, Adler P, Hindie V, Moncion T, et al.
Sci Data . 2019 Aug; 6(1):151. PMID: 31413325
Alzheimer's disease and other types of dementia are the top cause for disabilities in later life and various types of experiments have been performed to understand the underlying mechanisms of...