Michel Bottlaender
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Explore the profile of Michel Bottlaender including associated specialties, affiliations and a list of published articles.
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127
Citations
2269
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Recent Articles
11.
Maccioni L, Michelle C, Brusaferri L, Silvestri E, Bertoldo A, Schubert J, et al.
Front Neurosci
. 2024 Aug;
18:1395769.
PMID: 39104610
Introduction: Recent evidence suggests the blood-to-brain influx rate ( ) in imaging as a promising biomarker of blood-brain barrier () permeability alterations commonly associated with peripheral inflammation and heightened immune...
12.
Eysert F, Kinoshita P, Lagarde J, Lacas-Gervais S, Xicota L, Dorothee G, et al.
Acta Neuropathol Commun
. 2024 Jun;
12(1):90.
PMID: 38851733
Mitochondrial dysfunctions are key features of Alzheimer's disease (AD). The occurrence of these disturbances in the peripheral cells of AD patients and their potential correlation with disease progression are underinvestigated....
13.
Sarazin M, Lagarde J, El Haddad I, de Souza L, Bellier B, Potier M, et al.
Nat Aging
. 2024 Jun;
4(6):761-770.
PMID: 38839924
The cautious optimism following recent anti-amyloid therapeutic trials for Alzheimer's disease (AD) provides a glimmer of hope after years of disappointment. Although these encouraging results represent discernible progress, they also...
14.
Yazdan-Panah A, Bodini B, Soulier T, Veronese M, Bottlaender M, Tonietto M, et al.
EJNMMI Res
. 2024 May;
14(1):50.
PMID: 38801594
Background: Exploring the relationship between oxygen supply and myelin damage would benefit from a simultaneous quantification of myelin and cerebral blood flow (CBF) in the brain's white matter (WM). To...
15.
Lagarde J, Olivieri P, Tonietto M, Noiray C, Lehericy S, Valabregue R, et al.
Alzheimers Res Ther
. 2024 May;
16(1):97.
PMID: 38702802
Background: The locus coeruleus (LC) and the nucleus basalis of Meynert (NBM) are altered in early stages of Alzheimer's disease (AD). Little is known about LC and NBM alteration in...
16.
Soyer A, Goutal S, Leterrier S, Marie S, Larrat B, Selingue E, et al.
Ann Pharm Fr
. 2024 Apr;
82(5):822-829.
PMID: 38657857
Numerous studies suggest that blood-brain barrier (BBB) dysfunction may contribute to the progression of Alzheimer's disease (AD). Clinically available neuroimaging methods are needed for quantitative "scoring" of BBB permeability in...
17.
Auvity S, Vodovar D, Goutal S, Cisternino S, Chevillard L, Soyer A, et al.
J Cereb Blood Flow Metab
. 2023 Dec;
44(3):449-458.
PMID: 38097513
Among opioids, buprenorphine presents a favorable safety profile with a limited risk of respiratory depression. However, fatalities have been reported when buprenorphine is combined to a benzodiazepine. Potentiation of buprenorphine...
18.
Cheval M, Rodrigo S, Taussig D, Caille F, Petrescu A, Bottlaender M, et al.
Neurology
. 2023 Sep;
101(19):e1893-e1904.
PMID: 37748889
Background And Objectives: Translocator protein 18 kDa (TSPO) PET imaging is used to monitor glial activation. Recent studies have proposed TSPO PET as a marker of the epileptogenic zone (EZ)...
19.
Garland E, Dennett O, Lau L, Chatelet D, Bottlaender M, Nicoll J, et al.
J Neuroinflammation
. 2023 Aug;
20(1):186.
PMID: 37580767
The 18kD translocator protein (TSPO) is used as a positron emission tomography (PET) target to quantify neuroinflammation in patients. In Alzheimer's disease (AD), the cerebellum is the pseudo-reference region for...
20.
De Picker L, Morrens M, Branchi I, Haarman B, Terada T, Kang M, et al.
Brain Behav Immun
. 2023 Aug;
113:415-431.
PMID: 37543251
Introduction: The 18-kDa translocator protein (TSPO) is increasingly recognized as a molecular target for PET imaging of inflammatory responses in various central nervous system (CNS) disorders. However, the reported sensitivity...