Christine Coulon
Overview
Explore the profile of Christine Coulon including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
249
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Recent Articles
1.
Huvelle S, Pinon A, Coulon C, Bonasera T, Chapon C, Naninck T, et al.
ACS Omega
. 2024 Oct;
9(40):41732-41741.
PMID: 39398184
Positron emission tomography imaging using radiolabeled dolutegravir (DTG) is an interesting approach to understand the biodistribution of this antiretroviral drug at HIV-1 sanctuary sites. In the course of clinical translation,...
2.
Tournier N, Pottier G, Caille F, Coulon C, Goislard M, Jego B, et al.
Addict Biol
. 2020 Sep;
26(3):e12962.
PMID: 32896074
A large body of preclinical research has shown that neuroimmunity plays a key role in the deleterious effects of alcohol (ethanol) to the brain. Translational imaging techniques are needed to...
3.
Caille F, Gervais P, Auvity S, Coulon C, Marie S, Tournier N, et al.
Nucl Med Biol
. 2020 Jan;
84-85:20-27.
PMID: 31931306
Introduction: Glyburide is an approved anti-diabetes drug binding to the sulfonylurea receptors-1 (SUR-1) and substrate of solute carrier (SLC) transporters, which can be isotopically radiolabelled with carbon-11 for PET imaging....
4.
Goutal S, Langer O, Auvity S, Andrieux K, Coulon C, Caille F, et al.
Drug Deliv Transl Res
. 2018 Jan;
8(3):536-542.
PMID: 29294257
Elacridar (GF120918) is a highly potent inhibitor of both P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2), the main efflux transporters expressed at the blood-brain barrier (BBB). Elacridar shows very...
5.
Saba W, Goutal S, Auvity S, Kuhnast B, Coulon C, Kouyoumdjian V, et al.
Addict Biol
. 2017 Sep;
23(5):1000-1009.
PMID: 28944558
The effects of acute alcohol exposure to the central nervous system are hypothesized to involve the innate immune system. The neuroimmune response to an initial and acute alcohol exposure was...
6.
Peyronneau M, Saba W, Dolle F, Goutal S, Coulon C, Bottlaender M, et al.
Nucl Med Biol
. 2011 Dec;
39(3):347-59.
PMID: 22154687
Introduction: LBT-999, (E)-N-(4-fluorobut-2-enyl)-2β-carbomethoxy-3β-(4'-tolyl)nortropane, has been developed for PET imaging of the dopamine transporter. [(18)F]LBT-999 PET studies in baboons showed a lower brain uptake than [(11)C]LBT-999 and a high bone uptake,...
7.
Kuhnast B, Damont A, Hinnen F, Catarina T, Demphel S, Le Helleix S, et al.
Appl Radiat Isot
. 2011 Nov;
70(3):489-97.
PMID: 22104496
Imaging of TSPO 18 kDa with PET is more and more considered as a relevant biomarker of inflammation in numerous diseases. Development of new radiotracers for TSPO 18 kDa has...
8.
Saba W, Valette H, Peyronneau M, Bramoulle Y, Coulon C, Curet O, et al.
Synapse
. 2009 Sep;
64(1):61-9.
PMID: 19728365
[(11)C]SL-25.1188 [(S)-5-methoxymethyl-3-[6-(4,4,4-trifluorobutoxy)-benzo[d]isoxazol-3-yl]-oxazolidin-2-one], an oxazolidinone derivative, was characterized in baboons as a radioligand for the in vivo visualization of MAO-B using positron emission tomography (PET). After i.v. injection, [(11)C]SL25.1188 presented a...
9.
Kas A, Bottlaender M, Gallezot J, Vidailhet M, Villafane G, Gregoire M, et al.
J Cereb Blood Flow Metab
. 2009 Jun;
29(9):1601-8.
PMID: 19491921
Smoking is associated with a lower incidence of Parkinson's disease (PD), which might be related to a neuroprotective action of nicotine. Postmortem studies have shown a decrease of cerebral nicotinic...
10.
Besret L, Dolle F, Herard A, Guillermier M, Demphel S, Hinnen F, et al.
J Pharm Sci
. 2007 Sep;
97(7):2811-9.
PMID: 17786986
In vivo pharmacokinetic and brain binding characteristics of (+)-[(11)C]A-69024, a high-affinity-D1-selective dopamine receptor antagonist, were assessed with micro-PET and beta-microprobes in the rat and PET in the baboon. The biodistribution...