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Michal Weitman

Explore the profile of Michal Weitman including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 224
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Recent Articles
1.
Osher E, Anis Y, Singer-Shapiro R, Urshanski N, Unger T, Albeck S, et al.
Mol Ther Methods Clin Dev . 2024 Aug; 32(3):101300. PMID: 39211733
Tay-Sachs (TS) disease is a neurodegenerative disease resulting from mutations in the gene encoding the α-subunit (HEXA) of lysosomal β-hexosaminidase A (HexA). We report that (1) recombinant HEXA alone increased...
2.
Netzer A, Katzir I, Baruch Leshem A, Weitman M, Lampel A
Proc Natl Acad Sci U S A . 2023 Oct; 120(44):e2310569120. PMID: 37871222
Most biocatalytic processes in eukaryotic cells are regulated by subcellular microenvironments such as membrane-bound or membraneless organelles. These natural compartmentalization systems have inspired the design of synthetic compartments composed of...
3.
Khazma T, Grossman A, Guez-Haddad J, Feng C, Dabas H, Sain R, et al.
Cell Rep . 2023 Aug; 42(9):113026. PMID: 37635352
Wallerian axonal degeneration (WD) does not occur in the nematode C. elegans, in contrast to other model animals. However, WD depends on the NADase activity of SARM1, a protein that...
4.
Ben-Horin S, Salomon N, Karampekos G, Viazis N, Lahat A, Ungar B, et al.
Clin Gastroenterol Hepatol . 2023 Jun; 22(2):347-356.e6. PMID: 37302449
Background & Aims: We evaluated the efficacy of herbal combination of curcumin-QingDai (CurQD) in active ulcerative colitis (UC). Methods: Part I was an open-label trial of CurQD in patients with...
5.
Khazma T, Golan-Vaishenker Y, Guez-Haddad J, Grossman A, Sain R, Weitman M, et al.
Cell Mol Life Sci . 2023 Feb; 80(3):68. PMID: 36814037
No abstract available.
6.
Khazma T, Golan-Vaishenker Y, Guez-Haddad J, Grossman A, Sain R, Weitman M, et al.
Cell Mol Life Sci . 2022 Dec; 80(1):16. PMID: 36564647
In recent years, there has been growing interest in SARM1 as a potential breakthrough drug target for treating various pathologies of axon degeneration. SARM1-mediated axon degeneration relies on its TIR...
7.
Cohen Y, Weitman M
Pest Manag Sci . 2022 Nov; 79(3):1102-1112. PMID: 36334022
Background: Oxathiapiprolin (OXPT; FRAC code 49) is a new piperidinyl-thiazole isooxazoline anti-oomycete fungicide that targets oxysterol-binding proteins. The fungicide is known to translocate acropetally from root to shoot to protect...
8.
Weitman M, Eisenkraft A, TaShma Z, Makarovsky I, Last D, Daniels D, et al.
Sci Rep . 2022 Oct; 12(1):18078. PMID: 36302937
Organophosphates (OPs) are inhibitors of acetylcholinesterase and have deleterious effects on the central nervous system. Clinical manifestations of OP poisoning include convulsions, which represent an underlying toxic neuro-pathological process, leading...
9.
Aloni S, Perovic M, Weitman M, Cohen R, Oschatz M, Mastai Y
Nanoscale Adv . 2022 Sep; 1(12):4981-4988. PMID: 36133123
The synthesis of chiral nanoporous carbons based on chiral ionic liquids (CILs) of amino acids as precursors is described. Such unique precursors for the carbonization of CILs yield chiral carbonaceous...
10.
Massarano T, Baruch Leshem A, Weitman M, Lampel A
ACS Appl Mater Interfaces . 2022 Apr; 14(18):20520-20527. PMID: 35451309
Melanins are natural biopolymers that have remarkable properties including UV-protection, coloration, and antioxidant activity. Their biosynthesis is regulated both spatially and temporally and involves supramolecular templating and compartmentalization of enzymes...