Michaela Muller-McNicoll
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Explore the profile of Michaela Muller-McNicoll including associated specialties, affiliations and a list of published articles.
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38
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1139
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Recent Articles
1.
Zimmann F, McNicoll F, Thakur P, Blazikova M, Kubovciak J, Hernandez Canas M, et al.
Cell Mol Life Sci
. 2025 Mar;
82(1):103.
PMID: 40045025
Retinitis pigmentosa (RP) is a hereditary disorder caused by mutations in more than 70 different genes including those that encode proteins important for pre-mRNA splicing. Most RP-associated mutations in splicing...
2.
Oo J, Warwick T, Palfi K, Lam F, McNicoll F, Prieto-Garcia C, et al.
Nat Commun
. 2025 Jan;
16(1):131.
PMID: 39747144
The coordination of chromatin remodeling is essential for DNA accessibility and gene expression control. The highly conserved and ubiquitously expressed SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin remodeling complex plays a central role...
3.
Prieto-Garcia C, Matkovic V, Mosler T, Li C, Liang J, Oo J, et al.
Science
. 2024 Nov;
386(6723):768-776.
PMID: 39541449
RNA splicing enables the functional adaptation of cells to changing contexts. Impaired splicing has been associated with diseases, including retinitis pigmentosa, but the underlying molecular mechanisms and cellular responses remain...
4.
Rosenkranz R, Vraggalas S, Keller M, Sankaranarayanan S, McNicoll F, Lochli K, et al.
Nucleic Acids Res
. 2024 Aug;
52(19):11466-11480.
PMID: 39180404
Global warming poses a threat for crops, therefore, the identification of thermotolerance mechanisms is a priority. In plants, the core factors that regulate transcription under heat stress (HS) are well...
5.
von Ehr J, Oberstrass L, Yazgan E, Schnaubelt L, Blumel N, McNicoll F, et al.
J Biol Chem
. 2024 Jun;
300(7):107457.
PMID: 38866324
AT-rich interacting domain (ARID)-containing proteins, Arids, are a heterogeneous DNA-binding protein family involved in transcription regulation and chromatin processing. For the member Arid5a, no exact DNA-binding preference has been experimentally...
6.
Beck M, Covino R, Hanelt I, Muller-McNicoll M
Cell
. 2024 Feb;
187(3):545-562.
PMID: 38306981
Determining the structure and mechanisms of all individual functional modules of cells at high molecular detail has often been seen as equal to understanding how cells work. Recent technical advances...
7.
Arnold B, Riegger R, Okuda E, Sliskovic I, Keller M, Bakisoglu C, et al.
J Cell Biol
. 2023 Dec;
223(2).
PMID: 38108808
Nuclear RNA binding proteins (RBPs) are difficult to study because they often belong to large protein families and form extensive networks of auto- and crossregulation. They are highly abundant and...
8.
de Oliveira Freitas Machado C, Schafranek M, Bruggemann M, Hernandez Canas M, Keller M, Di Liddo A, et al.
Nucleic Acids Res
. 2023 Jan;
51(2):870-890.
PMID: 36620874
Hypoxia induces massive changes in alternative splicing (AS) to adapt cells to the lack of oxygen. Here, we identify the splicing factor SRSF6 as a key factor in the AS...
9.
Kirchhof L, Fouani Y, Knau A, Aslan G, Heumuller A, Wittig I, et al.
Noncoding RNA
. 2022 Jul;
8(4).
PMID: 35893232
Besides transcription, RNA decay accounts for a large proportion of regulated gene expression and is paramount for cellular functions. Classical RNA surveillance pathways, like nonsense-mediated decay (NMD), are also implicated...
10.
Tants J, Becker L, McNicoll F, Muller-McNicoll M, Schlundt A
Nucleic Acids Res
. 2022 Mar;
50(7):4083-4099.
PMID: 35357505
Control of posttranscriptional mRNA decay is a crucial determinant of cell homeostasis and differentiation. mRNA lifetime is governed by cis-regulatory elements in their 3' untranslated regions (UTR). Despite ongoing progress...