Michael Zogg
Overview
Explore the profile of Michael Zogg including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
15
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0
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Recent Articles
1.
Lemmens M, Perner J, Potgeter L, Zogg M, Thiruchelvam S, Muller M, et al.
Cytotherapy
. 2022 Nov;
25(1):59-67.
PMID: 36319564
Background: Engineered tissues and cell therapies based on human induced pluripotent stem cells (iPSCs) represent a promising approach for novel medicines. However, iPSC-derived cells and tissues may contain residual undifferentiated...
2.
Inderbinen S, Kley M, Zogg M, Sellner M, Fischer A, Kedzierski J, et al.
Toxicology
. 2022 Mar;
471:153159.
PMID: 35337918
Retinoic acid-related orphan receptor γt (RORγt) regulates immune responses and its impaired function contributes to inflammatory and autoimmune diseases and may promote skin cancer. Synthetic inverse RORγt agonists block the...
3.
Lemmens M, Fischer B, Zogg M, Rodrigues L, Kerr G, Del Rio-Espinola A, et al.
Mol Ther Methods Clin Dev
. 2021 Oct;
23:241-253.
PMID: 34703845
Off-target editing is one of the main safety concerns for the use of CRISPR-Cas9 genome editing in gene therapy. These unwanted modifications could lead to malignant transformation, which renders tumorigenicity...
4.
Inderbinen S, Zogg M, Kley M, Smiesko M, Odermatt A
Toxicol Appl Pharmacol
. 2021 Jan;
412:115387.
PMID: 33387577
11β-hydroxysteroid dehydrogenase 2 (11β-HSD2) converts active 11β-hydroxyglucocorticoids to their inactive 11-keto forms, thereby preventing inappropriate mineralocorticoid receptor activation by glucocorticoids. Disruption of 11β-HSD2 activity by genetic defects or inhibitors causes...