Michael Weiand
Overview
Explore the profile of Michael Weiand including associated specialties, affiliations and a list of published articles.
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7
Citations
2565
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Recent Articles
1.
Tran N, Heiner C, Weber K, Weiand M, Wilmot D, Xie J, et al.
Mol Ther Methods Clin Dev
. 2020 Aug;
18:639-651.
PMID: 32775498
The gene therapy field has been galvanized by two technologies that have revolutionized treating genetic diseases: vectors based on adeno-associated viruses (AAVs), and clustered regularly interspaced short palindromic repeats (CRISPR)-Cas...
2.
Tai P, Xie J, Fong K, Seetin M, Heiner C, Su Q, et al.
Mol Ther Methods Clin Dev
. 2018 May;
9:130-141.
PMID: 29766023
Recombinant adeno-associated virus (rAAV)-based gene therapy has entered a phase of clinical translation and commercialization. Despite this progress, vector integrity following production is often overlooked. Compromised vectors may negatively impact...
3.
Arnaout R, Lee W, Cahill P, Honan T, Sparrow T, Weiand M, et al.
PLoS One
. 2011 Aug;
6(8):e22365.
PMID: 21829618
Antibodies' protective, pathological, and therapeutic properties result from their considerable diversity. This diversity is almost limitless in potential, but actual diversity is still poorly understood. Here we use deep sequencing...
4.
Henn M, Sullivan M, Stange-Thomann N, Osburne M, Berlin A, Kelly L, et al.
PLoS One
. 2010 Feb;
5(2):e9083.
PMID: 20140207
Background: Bacterial viruses (phages) play a critical role in shaping microbial populations as they influence both host mortality and horizontal gene transfer. As such, they have a significant impact on...
5.
Lennon N, Lintner R, Anderson S, Alvarez P, Barry A, Brockman W, et al.
Genome Biol
. 2010 Feb;
11(2):R15.
PMID: 20137071
We present an automated, high throughput library construction process for 454 technology. Sample handling errors and cross-contamination are minimized via end-to-end barcoding of plasticware, along with molecular DNA barcoding of...
6.
Clark A, Eisen M, Smith D, Bergman C, Oliver B, Markow T, et al.
Nature
. 2007 Nov;
450(7167):203-18.
PMID: 17994087
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves the precision and sensitivity of evolutionary inference, producing more robust results than single-genome analyses can provide. The genomes of...
7.
Lindblad-Toh K, Wade C, Mikkelsen T, Karlsson E, Jaffe D, Kamal M, et al.
Nature
. 2005 Dec;
438(7069):803-19.
PMID: 16341006
Here we report a high-quality draft genome sequence of the domestic dog (Canis familiaris), together with a dense map of single nucleotide polymorphisms (SNPs) across breeds. The dog is of...