Michael W Young
Overview
Explore the profile of Michael W Young including associated specialties, affiliations and a list of published articles.
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Articles
47
Citations
2422
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Recent Articles
1.
Axelrod S, Li X, Sun Y, Lincoln S, Terceros A, ONeil J, et al.
Proc Natl Acad Sci U S A
. 2023 Oct;
120(42):e2309331120.
PMID: 37831742
Sleep is vital for most animals, yet its mechanism and function remain unclear. We found that permeability of the BBB (blood-brain barrier)-the organ required for the maintenance of homeostatic levels...
2.
Sletten T, Weaver M, Foster R, Gozal D, Klerman E, Rajaratnam S, et al.
Sleep Health
. 2023 Sep;
9(6):801-820.
PMID: 37684151
Objective: To develop and present consensus findings of the National Sleep Foundation sleep timing and variability panel regarding the impact of sleep timing variability on health and performance. Methods: The...
3.
Wang Z, Lincoln S, Nguyen A, Li W, Young M
Front Physiol
. 2022 Dec;
13:1048751.
PMID: 36467698
Genome-wide profiling of rhythmic gene expression has offered new avenues for studying the contribution of circadian clock to diverse biological processes. Sleep has been considered one of the most important...
4.
Li W, Wang Z, Syed S, Lyu C, Lincoln S, ONeil J, et al.
Nature
. 2021 Aug;
597(7875):239-244.
PMID: 34408325
Social isolation and loneliness have potent effects on public health. Research in social psychology suggests that compromised sleep quality is a key factor that links persistent loneliness to adverse health...
5.
Weaver M, Sletten T, Foster R, Gozal D, Klerman E, Rajaratnam S, et al.
Sleep Health
. 2021 Apr;
7(3):293-302.
PMID: 33795195
Polyphasic sleep is the practice of distributing multiple short sleep episodes across the 24-hour day rather than having one major and possibly a minor ("nap") sleep episode each day. While...
6.
Patke A, Young M, Axelrod S
Nat Rev Mol Cell Biol
. 2019 Nov;
21(2):67-84.
PMID: 31768006
To accommodate daily recurring environmental changes, animals show cyclic variations in behaviour and physiology, which include prominent behavioural states such as sleep-wake cycles but also a host of less conspicuous...
7.
Young M
Angew Chem Int Ed Engl
. 2018 Jul;
57(36):11532-11539.
PMID: 30003624
Living organisms have a biological clock that helps to prepare our physiology for the fluctuations of the day. Key research to elucidate the biological mechanisms of this regular adaptation, referred...
8.
Top D, ONeil J, Merz G, Dusad K, Crane B, Young M
Elife
. 2018 Apr;
7.
PMID: 29611807
In the circadian clock, Period (PER) and Timeless (TIM) proteins inhibit Clock-mediated transcription of and genes until PER is degraded by Doubletime/CK1 (DBT)-mediated phosphorylation, establishing a negative feedback loop. Multiple...
9.
Lin C, Top D, Manahan C, Young M, Crane B
Proc Natl Acad Sci U S A
. 2018 Mar;
115(15):3822-3827.
PMID: 29581265
Cryptochromes (CRYs) entrain the circadian clocks of plants and animals to light. Irradiation of the cryptochrome (dCRY) causes reduction of an oxidized flavin cofactor by a chain of conserved tryptophan...
10.