Michael W Duffel
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Explore the profile of Michael W Duffel including associated specialties, affiliations and a list of published articles.
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Articles
45
Citations
826
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Recent Articles
1.
Duffel M
Essays Biochem
. 2024 May;
68(4):541-553.
PMID: 38699885
The mammalian cytosolic sulfotransferases (SULTs) catalyze the sulfation of endocrine hormones as well as a broad array of drugs, environmental chemicals, and other xenobiotics. Many endocrine-disrupting chemicals (EDCs) interact with...
2.
Duffel M, Lehmler H
Crit Rev Toxicol
. 2024 Feb;
54(2):92-122.
PMID: 38363552
Polychlorinated biphenyls (PCBs) are persistent organic toxicants derived from legacy pollution sources and their formation as inadvertent byproducts of some current manufacturing processes. Metabolism of PCBs is often a critical...
3.
Zhang D, Saktrakulkla P, Marek R, Lehmler H, Wang K, Thorne P, et al.
Environ Sci Technol
. 2022 May;
56(10):6537-6547.
PMID: 35500099
Serum samples from 24 subjects (6 mother-daughter and 6 mother-son dyads) in a rural community (Columbus Junction, Iowa) and 24 subjects (6 mother-daughter and 6 mother-son dyads) in an urban...
4.
Duffel M, Tuttle K, Lehmler H, Robertson L
Environ Toxicol Pharmacol
. 2021 Oct;
88:103757.
PMID: 34688910
Polychlorinated biphenyls (PCBs) are persistent environmental contaminants that continue to be of concern due to their varied toxicities. Upon human exposure, many PCBs with lower numbers of chlorine atoms are...
5.
Zhang D, Saktrakulkla P, Tuttle K, Marek R, Lehmler H, Wang K, et al.
Environ Sci Technol
. 2021 Jan;
55(4):2473-2481.
PMID: 33502843
Polychlorinated biphenyls (PCBs) are persistent toxic chemicals with both legacy sources (e.g., Aroclors) and new sources (e.g., unintentional contaminants in some pigments and varnishes). PCB sulfates are derived from further...
6.
Sethi S, Morgan R, Feng W, Lin Y, Li X, Luna C, et al.
Environ Sci Technol
. 2019 Mar;
53(7):3948-3958.
PMID: 30821444
Polychlorinated biphenyls (PCBs) pose significant risk to the developing human brain; however, mechanisms of PCB developmental neurotoxicity (DNT) remain controversial. Two widely posited mechanisms are tested here using PCBs identified...
7.
Rodriguez E, Vanle B, Doorn J, Lehmler H, Robertson L, Duffel M
Environ Toxicol Pharmacol
. 2018 Jul;
62:69-78.
PMID: 29986280
Although neurotoxicity and hepatotoxicity have long been associated with exposure to polychlorinated biphenyls (PCBs), less is known about the selective toxicity of those hydroxylated PCBs (OH-PCBs) and PCB sulfates that...
8.
Parker V, Squirewell E, Lehmler H, Robertson L, Duffel M
Environ Toxicol Pharmacol
. 2018 Feb;
58:196-201.
PMID: 29408762
Polychlorinated biphenyls (PCBs) are ubiquitous environmental contaminants that are associated with varied adverse health effects. Lower chlorinated PCBs are prevalent in indoor and outdoor air and can be metabolized to...
9.
Li X, Holland E, Feng W, Zheng J, Dong Y, Pessah I, et al.
Environ Sci Pollut Res Int
. 2018 Jan;
25(17):16508-16521.
PMID: 29322390
Toxicological studies use "specialty chemicals" and, thus, should assess and report both identity and degree of purity (homogeneity) of the chemicals (or toxicants) under investigation to ensure that other scientists...
10.
Dhakal K, Gadupudi G, Lehmler H, Ludewig G, Duffel M, Robertson L
Environ Sci Pollut Res Int
. 2017 Jul;
25(17):16277-16290.
PMID: 28744683
Polychlorinated biphenyls (PCBs), a group of 209 congeners that differ in the number and position of chlorines on the biphenyl ring, are anthropogenic chemicals that belong to the persistent organic...