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Larry W Robertson

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Articles 144
Citations 2571
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Recent Articles
1.
Bullert A, Li X, Zhang C, Lee K, Pulliam C, Cagle B, et al.
bioRxiv . 2023 Aug; PMID: 37609242
Highlights: PCB 52 was present in adipose, brain, liver, and serum 3 weeks after PCB exposureLiver and serum contained hydroxylated, sulfated, and methylated PCB 52 metabolitesMetabolomics analysis revealed minor changes...
2.
Bullert A, Li X, Chunyun Z, Lee K, Pulliam C, Cagle B, et al.
Environ Toxicol Pharmacol . 2023 Aug; 102:104245. PMID: 37572994
The disposition and toxicity of lower chlorinated PCBs (LC-PCBs) with less than five chlorine substituents have received little attention. This study characterizes the distribution and metabolomic effects of PCB 52,...
3.
Gourronc F, Helm B, Robertson L, Chimenti M, Lehmler H, Ankrum J, et al.
Data Brief . 2022 Sep; 45:108571. PMID: 36131953
Exposure to polychlorinated biphenyls (PCBs) has been associated with the development of metabolic syndrome, a cluster of diseases that includes obesity, diabetes, liver steatosis, and cardiovascular problems. PCBs accumulate and...
4.
Gourronc F, Helm B, Robertson L, Chimenti M, Joachim-Lehmler H, Ankrum J, et al.
Toxicol In Vitro . 2022 May; 83:105396. PMID: 35618242
Polychlorinated biphenyls (PCBs) are persistent organic pollutants that accumulate in adipose tissue and have been associated with cardiometabolic disease. We have previously demonstrated that exposure of human preadipocytes to the...
5.
Eti N, Flor S, Iqbal K, Scott R, Klenov V, Gibson-Corley K, et al.
Toxicology . 2021 Dec; 466:153054. PMID: 34848246
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor involved in the regulation of biological responses to more planar aromatic hydrocarbons, like TCDD. We previously described the sequence of...
6.
Duffel M, Tuttle K, Lehmler H, Robertson L
Environ Toxicol Pharmacol . 2021 Oct; 88:103757. PMID: 34688910
Polychlorinated biphenyls (PCBs) are persistent environmental contaminants that continue to be of concern due to their varied toxicities. Upon human exposure, many PCBs with lower numbers of chlorine atoms are...
7.
Klenov V, Flor S, Ganesan S, Adur M, Eti N, Iqbal K, et al.
Toxicol Appl Pharmacol . 2021 Jul; 426:115639. PMID: 34256052
Polychlorinated biphenyls (PCBs) are endocrine disrupting chemicals with documented, though mechanistically ill-defined, reproductive toxicity. The toxicity of dioxin-like PCBs, such as PCB126, is mediated via the aryl hydrocarbon receptor (AHR)...
8.
Wang H, Adamcakova-Dodd A, Flor S, Gosse L, Klenov V, Stolwijk J, et al.
Environ Sci Technol . 2020 Dec; 54(24):15976-15985. PMID: 33256405
Few inhalation studies have explored the toxicity of environmentally relevant mixtures of polychlorinated biphenyls (PCBs). The manufacture of industrial PCBs was banned in 1978, but PCBs continue to be formed...
9.
Grimm F, Klaren W, Li X, Lehmler H, Karmakar M, Robertson L, et al.
Environ Health Perspect . 2020 Jul; 128(7):77008. PMID: 32701041
Background: Xenobiotic metabolism is complex, and accounting for bioactivation and detoxification processes of chemicals remains among the most challenging aspects for decision making with new approach methods data. Objectives: Considering...
10.
Williams A, Watt J, Robertson L, Gadupudi G, Osborn M, Soares M, et al.
Toxicol Sci . 2020 Mar; 175(1):113-125. PMID: 32119087
Epidemiological evidence links polychlorinated biphenyls (PCBs) to skeletal toxicity, however mechanisms whereby PCBs affect bone are poorly studied. In this study, coplanar PCB 126 (5 μmol/kg) or corn oil vehicle...