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Michael U Shiloh

Explore the profile of Michael U Shiloh including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 1572
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Recent Articles
11.
Stamm C, Pasko B, Chaisavaneeyakorn S, Franco L, Nair V, Weigele B, et al.
mSphere . 2019 Jun; 4(3). PMID: 31167949
(Mtb), the causative agent of tuberculosis, is one of the most successful human pathogens. One reason for its success is that Mtb can reside within host macrophages, a cell type...
12.
Shin H, Franco L, Nair V, Collins A, Shiloh M
PLoS One . 2017 Oct; 12(10):e0185945. PMID: 28982200
Mycobacterium tuberculosis, the causative agent of tuberculosis, is a major cause of morbidity and mortality worldwide. However, an effective vaccine for M. tuberculosis is lacking. We panned a phage display...
13.
Franco L, Nair V, Scharn C, Xavier R, Torrealba J, Shiloh M, et al.
Cell Host Microbe . 2017 Sep; 22(3):421-423. PMID: 28910640
No abstract available.
14.
Franco L, Nair V, Scharn C, Xavier R, Torrealba J, Shiloh M, et al.
Cell Host Microbe . 2016 Dec; 21(1):59-72. PMID: 28017659
During antibacterial autophagy, ubiquitination of intracellular bacteria recruits proteins that mediate bacterial delivery to the lysosome for degradation. Smurf1 is an E3 ubiquitin ligase whose role in selective bacterial autophagy...
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Nair V, Franco L, Zacharia V, Khan H, Stamm C, You W, et al.
Cell Rep . 2016 Jul; 16(5):1253-1258. PMID: 27452467
The prevailing paradigm is that tuberculosis infection is initiated when patrolling alveolar macrophages and dendritic cells within the terminal alveolus ingest inhaled Mycobacterium tuberculosis (Mtb). However, definitive data for this...
17.
Scharn C, Collins A, Nair V, Stamm C, Marciano D, Graviss E, et al.
J Immunol . 2016 May; 196(11):4641-9. PMID: 27183573
Mycobacterium tuberculosis, the causative agent of tuberculosis, is responsible for 1.5 million deaths annually. We previously showed that M. tuberculosis infection in mice induces expression of the CO-producing enzyme heme...
18.
Collins A, Cai H, Li T, Franco L, Li X, Nair V, et al.
Cell Host Microbe . 2015 Jun; 17(6):820-8. PMID: 26048137
Activation of the DNA-dependent cytosolic surveillance pathway in response to Mycobacterium tuberculosis infection stimulates ubiquitin-dependent autophagy and inflammatory cytokine production, and plays an important role in host defense against M....
19.
Stamm C, Collins A, Shiloh M
Immunol Rev . 2015 Feb; 264(1):204-19. PMID: 25703561
Mycobacterium tuberculosis (Mtb), the primary causative agent of human tuberculosis, has killed more people than any other bacterial pathogen in human history and remains one of the most important transmissible...
20.
Prokesch B, Shiloh M
Blood . 2014 Sep; 124(6):842. PMID: 25247213
No abstract available.