Michael T Marr 2nd
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Explore the profile of Michael T Marr 2nd including associated specialties, affiliations and a list of published articles.
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25
Citations
771
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Recent Articles
1.
Harris M, Marr 2nd M
Cell Rep
. 2023 Oct;
42(10):113283.
PMID: 37862172
Cells activate stress response pathways to survive adverse conditions. Such responses involve the inhibition of global cap-dependent translation. This inhibition is a block that essential transcripts must escape via alternative...
2.
Clark N, Harris M, Dahl W, Knotts Z, Marr 2nd M
Mol Cell Biol
. 2023 Sep;
43(10):485-499.
PMID: 37724583
IRES mediated translation initiation requires a different repertoire of factors than canonical cap-dependent translation. Treatments that inhibit the canonical translation factor EIF4G1 have little or no effect on the ability...
3.
Gartland S, Zeng B, Marr 2nd M
PLoS One
. 2022 Nov;
17(11):e0273590.
PMID: 36383505
Aging can be defined as the progressive loss of physiological homeostasis that leads to a decline in cellular and organismal function. In recent years, it has become clear that small...
4.
Harris M, Ho T, Fruchtman H, Garin M, Kubatin V, Lu T, et al.
Microbiol Resour Announc
. 2020 Nov;
9(45).
PMID: 33154018
, a fast-growing Gram-negative bacterium, is gaining interest as a platform for rapid biotechnology applications and metabolic engineering. Only a few bacteriophages that infect this bacterium have been identified. Here,...
5.
Royer L, Shangraw K, Herzog J, Pouvreau S, Marr 2nd M, Paradis S
Biochemistry
. 2019 May;
58(24):2710-2714.
PMID: 31141673
Nucleoside diphosphate kinases (Nmes or NDPKs) have been implicated in a multitude of cellular processes, including an important role in metastasis suppression, and several enzymatic activities have been assigned to...
6.
Royer L, Herzog J, Kenny K, Tzvetkova B, Cochrane J, Marr 2nd M, et al.
J Biol Chem
. 2018 Aug;
293(38):14798-14811.
PMID: 30072381
Ca/calmodulin-dependent protein kinase II (CaMKII) is a well-characterized, abundant protein kinase that regulates a diverse set of functions in a tissue-specific manner. For example, in heart muscle, CaMKII regulates Ca...
7.
Vasudevan D, Clark N, Sam J, Cotham V, Ueberheide B, Marr 2nd M, et al.
Cell Rep
. 2017 Nov;
21(8):2039-2047.
PMID: 29166596
Bacterial infection often leads to suppression of mRNA translation, but hosts are nonetheless able to express immune response genes through as yet unknown mechanisms. Here, we use a Drosophila model...
8.
Kenny K, Royer L, Moore A, Chen X, Marr 2nd M, Paradis S
Mol Cell Neurosci
. 2017 Oct;
85:190-201.
PMID: 29066292
The central nervous system has the remarkable ability to convert changes in the environment in the form of sensory experience into long-term alterations in synaptic connections and dendritic arborization, in...
9.
Kang M, Vasudevan D, Kang K, Kim K, Park J, Zhang N, et al.
J Cell Biol
. 2016 Dec;
216(1):115-129.
PMID: 27979906
Reduced amino acid availability attenuates mRNA translation in cells and helps to extend lifespan in model organisms. The amino acid deprivation-activated kinase GCN2 mediates this response in part by phosphorylating...
10.
Donovan M, Marr 2nd M
J Biol Chem
. 2016 Jul;
291(36):19042-50.
PMID: 27435672
Maintaining protein homeostasis is critical for survival at the cellular and organismal level (Morimoto, R. I. (2011) Cold Spring Harb. Symp. Quant. Biol. 76, 91-99). Cells express a family of...