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Michael Schuliga

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Articles 36
Citations 964
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Recent Articles
1.
Read J, Reid A, Thomson C, Plit M, Mejia R, Knight D, et al.
Clin Sci (Lond) . 2024 Apr; 138(8):537-554. PMID: 38577922
Patients with pulmonary fibrosis (PF) often experience exacerbations of their disease, characterised by a rapid, severe deterioration in lung function that is associated with high mortality. Whilst the pathobiology of...
2.
Blokland K, Nizamoglu M, Habibie H, Borghuis T, Schuliga M, Melgert B, et al.
Front Pharmacol . 2022 Nov; 13:989169. PMID: 36408252
In fibrosis remodelling of ECM leads to changes in composition and stiffness. Such changes can have a major impact on cell functions including proliferation, secretory profile and differentiation. Several studies...
3.
George P, Reed A, Desai S, Devaraj A, Faiez T, Laverty S, et al.
Sci Transl Med . 2022 Nov; 14(671):eabo5795. PMID: 36383686
Interstitial lung disease and associated fibrosis occur in a proportion of individuals who have recovered from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection through unknown mechanisms. We studied individuals...
4.
Schuliga M, Madala S
Am J Respir Cell Mol Biol . 2022 Mar; 66(5):465-467. PMID: 35238730
No abstract available.
5.
Waters D, Schuliga M, Pathinayake P, Wei L, Tan H, Blokland K, et al.
Biomedicines . 2021 Sep; 9(9). PMID: 34572347
Idiopathic pulmonary fibrosis (IPF) is a chronic disease characterised by a dense fibrosing of the lung parenchyma. An association between IPF and cellular senescence is well established and several studies...
6.
Schuliga M, Kanwal A, Read J, Blokland K, Burgess J, Prele C, et al.
Am J Physiol Lung Cell Mol Physiol . 2021 Sep; 321(5):L859-L871. PMID: 34524912
Alveolar epithelial cell (AEC) senescence is implicated in the pathogenesis of idiopathic pulmonary fibrosis (IPF). Mitochondrial dysfunction including release of mitochondrial DNA (mtDNA) is a feature of senescence, which led...
7.
Schuliga M, Read J, Knight D
Ageing Res Rev . 2021 Jul; 70:101405. PMID: 34242806
Age is a major risk factor for chronic respiratory diseases such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and certain phenotypes of asthma. The recent COVID-19 pandemic...
8.
Blokland K, Habibie H, Borghuis T, Teitsma G, Schuliga M, Melgert B, et al.
Cells . 2021 Jul; 10(7). PMID: 34209854
Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease with poor survival. Age is a major risk factor, and both alveolar epithelial cells and lung fibroblasts in this disease exhibit...
9.
Blokland K, Pouwels S, Schuliga M, Knight D, Burgess J
Clin Sci (Lond) . 2020 Oct; 134(20):2681-2706. PMID: 33084883
The extracellular matrix (ECM) is a complex network of macromolecules surrounding cells providing structural support and stability to tissues. The understanding of the ECM and the diverse roles it plays...
10.
Blokland K, Waters D, Schuliga M, Read J, Pouwels S, Grainge C, et al.
Pharmaceutics . 2020 Apr; 12(4). PMID: 32344567
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease marked by excessive accumulation of lung fibroblasts (LFs) and collagen in the lung parenchyma. The mechanisms that underlie IPF pathophysiology are...