Michael S Phillips
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Explore the profile of Michael S Phillips including associated specialties, affiliations and a list of published articles.
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Recent Articles
41.
Phillips M, Hihi A, Van Rooij T, Smith A, James S, Marsh S, et al.
Pharmacogenomics
. 2008 Oct;
9(10):1391-6.
PMID: 18855527
The Génome Québec and Montreal Heart Institute Pharmacogenomics Centre (Montreal, Canada), created in 2006, is a translational pharmacogenomics platform whose main objectives are to conduct pharmacogenomics research, provide pharmacogenomics services...
42.
King C, Porche-Sorbet R, Gage B, Ridker P, Renaud Y, Phillips M, et al.
Am J Clin Pathol
. 2008 May;
129(6):876-83.
PMID: 18480003
Initiation of warfarin therapy is associated with bleeding owing to its narrow therapeutic window and unpredictable therapeutic dose. Pharmacogenetic-based dosing algorithms can improve accuracy of initial warfarin dosing but require...
43.
Sabeti P, Fry B, Lohmueller J, Hostetter E, Cotsapas C, Xie X, et al.
Nature
. 2007 Oct;
449(7164):913-8.
PMID: 17943131
With the advent of dense maps of human genetic variation, it is now possible to detect positive natural selection across the human genome. Here we report an analysis of over...
44.
Frazer K, Ballinger D, Cox D, Hinds D, Stuve L, Boudreau A, et al.
Nature
. 2007 Oct;
449(7164):851-61.
PMID: 17943122
We describe the Phase II HapMap, which characterizes over 3.1 million human single nucleotide polymorphisms (SNPs) genotyped in 270 individuals from four geographically diverse populations and includes 25-35% of common...
45.
Montpetit A, Phillips M, Mongrain I, Lemieux R, St-Louis M
Transfusion
. 2006 May;
46(5):841-8.
PMID: 16686853
Background: ABO and D phenotyping of both blood donors and patients receiving transfusions is routinely performed by blood banks to ensure compatibility. These analyses are performed by antibody-based agglutination assays....
46.
Samandari T, Malakmadze N, Balter S, Perz J, Khristova M, Swetnam L, et al.
Infect Control Hosp Epidemiol
. 2005 Oct;
26(9):745-50.
PMID: 16209380
Objectives: To determine whether hepatitis B virus (HBV) transmission occurred among patients visiting a physician's office and to evaluate potential transmission mechanisms. Design: Serologic survey, retrospective cohort study, and observation...
47.
Miller R, Phillips M, Jo I, Donaldson M, Studebaker J, Addleman N, et al.
Genomics
. 2005 Jun;
86(2):117-26.
PMID: 15961272
Here we report a large, extensively characterized set of single-nucleotide polymorphisms (SNPs) covering the human genome. We determined the allele frequencies of 55,018 SNPs in African Americans, Asians (Japanese-Chinese), and...
48.
Terra S, Pauly D, Lee C, Patterson J, Adams K, Schofield R, et al.
Clin Pharmacol Ther
. 2005 Mar;
77(3):127-37.
PMID: 15735607
Objective: beta-Blockers require careful initiation and titration when used in patients with heart failure. Some patients tolerate beta-blocker therapy initiation without difficulty, whereas in other patients this period presents clinical...
49.
Zineh I, Beitelshees A, Gaedigk A, Walker J, Pauly D, Eberst K, et al.
Clin Pharmacol Ther
. 2004 Dec;
76(6):536-44.
PMID: 15592325
Objective: Beta-Blocker use can be associated with adverse effects that may have an impact on adherence or harm patients. The commonly prescribed beta-blocker metoprolol is metabolized by the polymorphic cytochrome...
50.
Mitra N, Ye T, Smith A, Chuai S, Kirchhoff T, Peterlongo P, et al.
Cancer Res
. 2004 Nov;
64(21):8116-25.
PMID: 15520224
With the large numbers of single nucleotide polymorphisms (SNPs) available and new technologies that permit high throughput genotyping, we have investigated the possibility of the localization of disease genes with...