Michael R Thomas
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Explore the profile of Michael R Thomas including associated specialties, affiliations and a list of published articles.
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25
Citations
433
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Recent Articles
1.
Ayrton J, Ho C, Zhang H, Chudasama V, Frank S, Thomas M
Nanoscale
. 2024 Oct;
16(42):19881-19896.
PMID: 39382227
The ease of expression and engineering of single domain antibodies, known as nanobodies, make them attractive alternatives to conventional antibodies in point-of-care diagnostics such as lateral flow assays. In lateral...
2.
Barriga H, Pence I, Holme M, Doutch J, Penders J, Nele V, et al.
Adv Mater
. 2022 Mar;
34(26):e2200839.
PMID: 35358374
Lipid nanoparticles (LNPs) are versatile structures with tunable physicochemical properties that are ideally suited as a platform for vaccine delivery and RNA therapeutics. A key barrier to LNP rational design...
3.
Miller B, Thomas M, Banner M, Kim J, Chen Y, Wei Q, et al.
Biosens Bioelectron
. 2022 Mar;
207:114133.
PMID: 35316759
Lateral flow tests, commonly based on metal plasmonic nanoparticles, are rapid, robust, and low-cost. However, improvements in analytical sensitivity are required to allow detection of low-abundance biomarkers, for example detection...
4.
Nele V, Holme M, Rashid M, Barriga H, Le T, Thomas M, et al.
Langmuir
. 2021 Sep;
37(40):11909-11921.
PMID: 34581180
Short-chain alcohols (i.e., ethanol) can induce membrane interdigitation in saturated-chain phosphatidylcholines (PCs). In this process, alcohol molecules intercalate between phosphate heads, increasing lateral separation and favoring hydrophobic interactions between opposing...
5.
Richards D, Thomas M, Szijj P, Foote J, Chen Y, Nogueira J, et al.
Nanoscale
. 2021 Jun;
13(27):11921-11931.
PMID: 34190286
Novel methods for introducing chemical and biological functionality to the surface of gold nanoparticles serve to increase the utility of this class of nanomaterials across a range of applications. To...
6.
Xianyu Y, Lin Y, Chen Q, Belessiotis-Richards A, Stevens M, Thomas M
Angew Chem Int Ed Engl
. 2021 Feb;
60(18):9891-9896.
PMID: 33590604
Iodide-mediated surface etching can tailor the surface plasmon resonance of gold nanostars through etching of the high-energy facets of the nanoparticle protrusions in a rapid and sensitive way. By exploring...
7.
Kim N, Kim E, Kim H, Thomas M, Najer A, Stevens M
Adv Mater
. 2021 Feb;
33(11):e2007738.
PMID: 33554370
Probing endogenous molecular profiles is of fundamental importance to understand cellular function and processes. Despite the promise of programmable nucleic-acid-based aptasensors across the breadth of biomolecular detection, target-responsive aptasensors enabling...
8.
Kim N, Thomas M, Bergholt M, Pence I, Seong H, Charchar P, et al.
Nat Commun
. 2020 Jan;
11(1):207.
PMID: 31924755
Label-free surface-enhanced Raman spectroscopy (SERS) can interrogate systems by directly fingerprinting their components' unique physicochemical properties. In complex biological systems however, this can yield highly overlapping spectra that hinder sample...
9.
Wang S, Lin Y, Nielsen M, Song C, Thomas M, Spicer C, et al.
Nanoscale
. 2019 Aug;
11(36):16801-16809.
PMID: 31469380
Understanding the mechanisms behind crystal nucleation and growth is a fundamental requirement for the design and production of bespoke nanomaterials with controlled sizes and morphologies. Herein, we select gold (Au)...
10.
Nele V, Holme M, Kauscher U, Thomas M, Doutch J, Stevens M
Langmuir
. 2019 Apr;
35(18):6064-6074.
PMID: 30977658
Liposomes are well-established systems for drug delivery and biosensing applications. The design of a liposomal carrier requires careful choice of lipid composition and formulation method. These determine many vesicle properties...