Michael R Drew
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Explore the profile of Michael R Drew including associated specialties, affiliations and a list of published articles.
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45
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2228
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Recent Articles
21.
Huckleberry K, Shue F, Copeland T, Chitwood R, Yin W, Drew M
Neuropsychopharmacology
. 2018 Jun;
43(12):2487-2496.
PMID: 29941977
The hippocampus contains one of the few neurogenic niches within the adult brain-the subgranular zone of the dentate gyrus. The functional significance of adult-born neurons in this region has been...
22.
Tsutsui-Kimura I, Natsubori A, Mori M, Kobayashi K, Drew M, de Kerchove dExaerde A, et al.
Curr Biol
. 2017 Oct;
27(19):3042-3048.e4.
PMID: 28966085
The ventral striatum (VS) is a key brain center regulating reward-oriented behavior [1-4]. The VS can be anatomically divided into medial (VMS) and lateral (VLS) portions based on cortical input...
23.
Bernier B, Lacagnina A, Ayoub A, Shue F, Zemelman B, Krasne F, et al.
J Neurosci
. 2017 May;
37(26):6359-6371.
PMID: 28546308
Dentate gyrus (DG) is widely thought to provide a teaching signal that enables hippocampal encoding of memories, but its role during retrieval is poorly understood. Some data and models suggest...
24.
Drew M, Huckleberry K
Neurotherapeutics
. 2017 May;
14(3):646-661.
PMID: 28488160
Adult hippocampal neurogenesis (AHN) occurs in humans and every other mammalian species examined. Evidence that AHN is stimulated by a variety of treatments and behaviors with anxiolytic properties has sparked...
25.
Tsutsui-Kimura I, Takiue H, Yoshida K, Xu M, Yano R, Ohta H, et al.
Nat Commun
. 2017 Feb;
8:14304.
PMID: 28145402
Impaired motivation is present in a variety of neurological disorders, suggesting that decreased motivation is caused by broad dysfunction of the nervous system across a variety of circuits. Based on...
26.
Drew M, Walsh C, Balsam P
J Exp Psychol Anim Learn Cogn
. 2017 Jan;
43(1):1-14.
PMID: 28045291
Previous research suggests that extinction learning is temporally specific. Changing the conditioned stimulus (CS) duration between training and extinction can facilitate the loss of the conditioned response (CR) within the...
27.
Huckleberry K, Ferguson L, Drew M
Learn Mem
. 2016 Dec;
23(12):703-709.
PMID: 27918275
There is growing interest in generalization of learned contextual fear, driven in part by the hypothesis that mood and anxiety disorders stem from impaired hippocampal mechanisms of fear generalization and...
28.
Wolfe S, Workman E, Heaney C, Niere F, Namjoshi S, Cacheaux L, et al.
Nat Commun
. 2016 Sep;
7:12867.
PMID: 27666021
Alcohol promotes lasting neuroadaptive changes that may provide relief from depressive symptoms, often referred to as the self-medication hypothesis. However, the molecular/synaptic pathways that are shared by alcohol and antidepressants...
29.
Huckleberry K, Kane G, Mathis R, Cook S, Clutton J, Drew M
Front Syst Neurosci
. 2015 Sep;
9:118.
PMID: 26347620
Thousands of neurons are born each day in the dentate gyrus (DG), but many of these cells die before reaching maturity. Both death and survival of adult-born neurons are regulated...
30.
Seo D, Carillo M, Chih-Hsiung Lim S, Tanaka K, Drew M
J Neurosci
. 2015 Aug;
35(32):11330-45.
PMID: 26269640
Significance Statement: The role of adult hippocampal neurogenesis in fear learning is controversial, with some studies suggesting neurogenesis is needed for aspects of fear learning and others suggesting it is...