Michael R Williamson
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Explore the profile of Michael R Williamson including associated specialties, affiliations and a list of published articles.
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22
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347
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Recent Articles
1.
Williamson M, Kwon W, Woo J, Ko Y, Maleki E, Yu K, et al.
Nature
. 2024 Nov;
637(8045):478-486.
PMID: 39506118
The physical manifestations of memory formation and recall are fundamental questions that remain unresolved. At the cellular level, ensembles of neurons called engrams are activated by learning events and control...
2.
Mihelic S, Engelmann S, Sadr M, Jafari C, Zhou A, Woods A, et al.
J Cereb Blood Flow Metab
. 2024 Aug;
44(12):1441-1458.
PMID: 39113424
This manuscript quantitatively investigates remodeling dynamics of the cortical microvascular network (thousands of connected capillaries) following photothrombotic ischemia (cubic millimeter volume, imaged weekly) using a novel two-photon angiography and high...
3.
Chen H, He P, McDonald M, Williamson M, Varadharajan S, Lozzi B, et al.
Nature
. 2024 Jul;
632(8026):903-910.
PMID: 39085609
Bidirectional communication between tumours and neurons has emerged as a key facet of the tumour microenvironment that drives malignancy. Another hallmark feature of cancer is epigenomic dysregulation, in which alterations...
4.
Williamson M, Deneen B
Immunity
. 2024 May;
57(5):938-940.
PMID: 38749396
Astrocytes respond to all forms of central nervous system maladies. In a recent issue of Nature, Lee et al. demonstrate that astrocytes encode inflammatory stimuli as epigenetic memory, which strengthens...
5.
Kwon W, Choi D, Yu K, Williamson M, Murali S, Ko Y, et al.
Int J Mol Sci
. 2024 Jan;
25(2).
PMID: 38256095
Astrocytes are the most abundant glial cell type in the central nervous system, and they play a crucial role in normal brain function. While gliogenesis and glial differentiation occur during...
6.
Williamson M, Le S, Franzen R, Donlan N, Rosow J, Nicot-Cartsonis M, et al.
Nat Commun
. 2023 Oct;
14(1):6341.
PMID: 37816732
Stroke enhances proliferation of neural precursor cells within the subventricular zone (SVZ) and induces ectopic migration of newborn cells towards the site of injury. Here, we characterize the identity of...
7.
Huang-Hobbs E, Cheng Y, Ko Y, Luna-Figueroa E, Lozzi B, Taylor K, et al.
Nature
. 2023 Jun;
619(7971):844-850.
PMID: 37380778
The tumour microenvironment plays an essential role in malignancy, and neurons have emerged as a key component of the tumour microenvironment that promotes tumourigenesis across a host of cancers. Recent...
8.
Engelmann S, Zhou A, Hassan A, Williamson M, Jarrett J, Perillo E, et al.
Biomed Opt Express
. 2022 May;
13(4):1888-1898.
PMID: 35519268
Here we introduce a fiber amplifier and a diamond Raman laser that output high powers (6.5 W, 1.3 W) at valuable wavelengths (1060 nm, 1250 nm) for two-photon excitation of...
9.
Mihelic S, Sikora W, Hassan A, Williamson M, Jones T, Dunn A
PLoS Comput Biol
. 2021 Oct;
17(10):e1009451.
PMID: 34624013
Recent advances in two-photon fluorescence microscopy (2PM) have allowed large scale imaging and analysis of blood vessel networks in living mice. However, extracting network graphs and vector representations for the...
10.
Williamson M, Fuertes C, Dunn A, Drew M, Jones T
Cell Rep
. 2021 Apr;
35(4):109048.
PMID: 33910014
Brain injury causes astrocytes to assume a reactive state that is essential for early tissue protection, but how reactive astrocytes affect later reparative processes is incompletely understood. In this study,...