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Michael Mayne

Explore the profile of Michael Mayne including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 218
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Recent Articles
1.
Grant J, Parker K, Moore C, Keddy P, Mayne M, Robertson G
Neurochem Res . 2013 Feb; 38(4):847-56. PMID: 23397285
X-linked inhibitor of apoptosis (XIAP) protects and preserves the function of neurons in both in vitro and in vivo models of excitotoxicity. Since calcium (Ca(2+)) overload is a pivotal event...
2.
Supnet C, Noonan C, Richard K, Bradley J, Mayne M
J Neurochem . 2009 Nov; 112(2):356-65. PMID: 19903243
The cellular pathology of Alzheimer's disease is progressive and protracted leading eventually to considerable neuronal death. The underlying mechanisms of the pathology are complex but changes in the control of...
3.
Soundararajan R, Wishart A, Rupasinghe H, Arcellana-Panlilio M, Nelson C, Mayne M, et al.
J Biol Chem . 2007 Nov; 283(4):2231-45. PMID: 18032389
The flavonoid quercetin 3-glucoside (Q3G) protected SH-SY5Y, HEK293, and MCF-7 cells against hydrogen peroxide-induced oxidative stress. cDNA microarray studies suggested that Q3G-pretreated cells subjected to oxidative stress up-regulate the expression...
4.
Supnet C, Grant J, Kong H, Westaway D, Mayne M
J Biol Chem . 2006 Oct; 281(50):38440-7. PMID: 17050533
Disruption of intracellular calcium homeostasis precedes the neurodegeneration that occurs in Alzheimer disease (AD). Of the many neuronal calcium-regulating proteins, we focused on endoplasmic reticulum (ER)-resident ryanodine receptors (RyRs) because...
5.
Kaput J, Ordovas J, Ferguson L, van Ommen B, Rodriguez R, Allen L, et al.
Br J Nutr . 2005 Nov; 94(5):623-32. PMID: 16277761
Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into...
6.
McLaren P, Mayne M, Rosser S, Moffatt T, Becker K, Plummer F, et al.
Clin Diagn Lab Immunol . 2004 Sep; 11(5):977-82. PMID: 15358662
Advances in microarray technology have allowed for the monitoring of thousands of genes simultaneously. This technology is of particular interest to immunologists studying infectious diseases, because it provides tremendous potential...
7.
Mayne M, Moffatt T, Kong H, McLaren P, Fowke K, Becker K, et al.
Eur J Immunol . 2004 Mar; 34(4):1217-27. PMID: 15048733
DNA microarray profiling of CD4(+) and CD8(+) cells from non-treated relapsing and remitting multiple sclerosis (MS) patients determined that the cytoplasmic binding partner of fragile X protein (CYFIP2, also called...
8.
Kong H, Baerbig Q, Duncan L, Shepel N, Mayne M
J Neurovirol . 2003 Sep; 9(5):539-50. PMID: 13129768
Accumulating evidence suggests that human herpesvirus type 6 (HHV-6) plays a pathogenic role in diseases of the central nervous system including multiple sclerosis (MS). Recent studies have indicated that HHV-6...
9.
Cermelli C, Berti R, Soldan S, Mayne M, Dambrosia J, Ludwin S, et al.
J Infect Dis . 2003 Apr; 187(9):1377-87. PMID: 12717618
The frequency of human herpesvirus 6 (HHV-6) DNA was assessed in autopsy material from multiple sclerosis (MS) plaques and normal-appearing white matter (NAWM) from brains of persons with MS, healthy...