Michael M C Sun
Overview
Explore the profile of Michael M C Sun including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
574
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Recent Articles
1.
Sun M, Beam K, Cerveny C, Hamblett K, Blackmore R, Torgov M, et al.
Bioconjug Chem
. 2005 Sep;
16(5):1282-90.
PMID: 16173809
Site-specific conjugation of small molecules and enzymes to monoclonal antibodies has broad utility in the formation of conjugates for therapeutic, diagnostic, or structural applications. Precise control over the location of...
2.
Sanderson R, Hering M, James S, Sun M, Doronina S, Siadak A, et al.
Clin Cancer Res
. 2005 Feb;
11(2 Pt 1):843-52.
PMID: 15701875
Effective antibody-drug conjugates (ADC) combine high drug-linker stability in circulation and efficient intratumoral release of drug. Conjugation of monomethyl auristatin E (MMAE) to the anti-CD30 monoclonal antibody (mAb), cAC10, produced...
3.
Hamblett K, Senter P, Chace D, Sun M, Lenox J, Cerveny C, et al.
Clin Cancer Res
. 2004 Oct;
10(20):7063-70.
PMID: 15501986
Purpose: An antibody-drug conjugate consisting of monomethyl auristatin E (MMAE) conjugated to the anti-CD30 monoclonal antibody (mAb) cAC10, with eight drug moieties per mAb, was previously shown to have potent...