Michael Lotz
Overview
Explore the profile of Michael Lotz including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
467
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Recent Articles
1.
Chassin C, Kocur M, Pott J, Duerr C, Gutle D, Lotz M, et al.
Cell Host Microbe
. 2010 Oct;
8(4):358-68.
PMID: 20951969
After birth, the intestinal mucosa undergoes a dramatic transition from a sterile protected site to an environmentally exposed and permanently colonized surface. The mechanisms that facilitate this transition are ill...
2.
Menard S, Forster V, Lotz M, Gutle D, Duerr C, Gallo R, et al.
J Exp Med
. 2008 Jan;
205(1):183-93.
PMID: 18180308
Paneth cell-derived enteric antimicrobial peptides provide protection from intestinal infection and maintenance of enteric homeostasis. Paneth cells, however, evolve only after the neonatal period, and the antimicrobial mechanisms that protect...
3.
Hormonal control of the renal immune response and antibacterial host defense by arginine vasopressin
Chassin C, Hornef M, Bens M, Lotz M, Goujon J, Vimont S, et al.
J Exp Med
. 2007 Oct;
204(12):2837-52.
PMID: 17967904
Ascending urinary tract infection (UTI) and pyelonephritis caused by uropathogenic Escherichia coli (UPEC) are very common infections that can cause severe kidney damage. Collecting duct cells, the site of hormonally...
4.
Lotz M, Konig T, Menard S, Gutle D, Bogdan C, Hornef M
Immunology
. 2007 May;
122(3):306-15.
PMID: 17511808
Cytokines with anti-inflammatory properties have been implicated in the prevention of inappropriate immune activation by commensal bacteria in the intestinal tract. Here, we analysed receptor expression, cellular signalling, and the...
5.
Lotz M, Menard S, Hornef M
Int J Med Microbiol
. 2007 Apr;
297(5):379-92.
PMID: 17459768
The discovery of transcriptionally activating receptors for microbial structures has provided a deeper understanding of how the immune system manages to sense and localize the presence of harmful microbes and...
6.
Lotz M, Gutle D, Walther S, Menard S, Bogdan C, Hornef M
J Exp Med
. 2006 Apr;
203(4):973-84.
PMID: 16606665
The role of innate immune recognition by intestinal epithelial cells (IECs) in vivo is ill-defined. Here, we used highly enriched primary IECs to analyze Toll-like receptor (TLR) signaling and mechanisms...
7.
Su Y, Herzog S, Lotz M, Feldhahn N, Muschen M, Jumaa H
Eur J Immunol
. 2004 Nov;
34(12):3614-22.
PMID: 15549729
Successful recombination of the heavy-chain locus in developing B cells results in the expression of the pre-BCR, which induces the proliferation and expansion of pre-B cells. To avoid uncontrolled proliferation,...
8.
Jumaa H, Bossaller L, Portugal K, Storch B, Lotz M, Flemming A, et al.
Nature
. 2003 May;
423(6938):452-6.
PMID: 12761551
Acute lymphoblastic leukaemia (ALL) is the commonest form of childhood malignancy, and most cases arise from B-cell clones arrested at the pre-B-cell stage of differentiation. The molecular events that arrest...