Mathias W Hornef
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Explore the profile of Mathias W Hornef including associated specialties, affiliations and a list of published articles.
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86
Citations
3500
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Recent Articles
1.
Narasimhan H, Richter M, Shakiba R, Papaioannou N, Stehle C, Ravi Rengarajan K, et al.
Proc Natl Acad Sci U S A
. 2025 Feb;
122(9):e2417308122.
PMID: 39993193
Conventional dendritic cells (cDCs) are potent antigen-presenting cells (APCs) that integrate signals from their environment allowing them to direct situation-adapted immunity. Thereby they harbor great potential for being targeted in...
2.
Schlosser S, Ullrich A, Modares N, Schmitz M, Schoneich J, Zhang K, et al.
Proc Natl Acad Sci U S A
. 2025 Jan;
122(1):e2403344122.
PMID: 39793046
Postnatal establishment of enteric metabolic, host-microbial and immune homeostasis is the result of precisely timed and tightly regulated developmental and adaptive processes. Here, we show that infection with the invasive...
3.
Li P, Schulte J, Wurpts G, Hornef M, Wolz C, Yazdi A, et al.
Int J Mol Sci
. 2024 Sep;
25(17).
PMID: 39273114
acts both as a colonizing commensal bacterium and invasive pathogen. Nasal colonization is associated with an increased risk of infection caused by the identical strain. In patients with atopic dermatitis...
4.
Zhang K, Repnik U, Diab N, Friske D, Putz A, Bachmann A, et al.
J Exp Med
. 2024 Feb;
221(3).
PMID: 38305765
The intestinal epithelium is the first line of defense against enteric pathogens. Removal of infected cells by exfoliation prevents mucosal translocation and systemic infection in the adult host, but is...
5.
Kister B, Viehof A, Rolle-Kampczyk U, Schwentker A, Treichel N, Jennings S, et al.
iScience
. 2023 Oct;
26(10):107922.
PMID: 37817939
Bile acid (BA) metabolism is a complex system that includes a wide variety of primary and secondary, as well as conjugated and unconjugated BAs that undergo continuous enterohepatic circulation (EHC)....
6.
Schmitz S, Helmedag M, Kroh A, Heise D, Klinge U, Lambertz A, et al.
Biomedicines
. 2023 Jul;
11(7).
PMID: 37509722
Background: Synthetic mesh material is of great importance for surgical incisional hernia repair. The physical and biochemical characteristics of the mesh influence mechanical stability and the foreign body tissue reaction....
7.
Pabst O, Hornef M, Schaap F, Cerovic V, Clavel T, Bruns T
Nat Rev Gastroenterol Hepatol
. 2023 Apr;
20(7):447-461.
PMID: 37085614
The gut and the liver are characterized by mutual interactions between both organs, the microbiome, diet and other environmental factors. The sum of these interactions is conceptualized as the gut-liver...
8.
Torow N, Hand T, Hornef M
Immunity
. 2023 Mar;
56(3):485-499.
PMID: 36921575
The mucosal immune system of neonates goes through successive, non-redundant phases that support the developmental needs of the infant and ultimately establish immune homeostasis. These phases are informed by environmental...
9.
Kennedy K, de Goffau M, Perez-Munoz M, Arrieta M, Backhed F, Bork P, et al.
Nature
. 2023 Jan;
613(7945):639-649.
PMID: 36697862
Whether the human fetus and the prenatal intrauterine environment (amniotic fluid and placenta) are stably colonized by microbial communities in a healthy pregnancy remains a subject of debate. Here we...
10.
Teichmann P, Both A, Wolz C, Hornef M, Rohde H, Yazdi A, et al.
Front Microbiol
. 2022 May;
13:896311.
PMID: 35558117
The virulence factors of the opportunistic human pathogen have been a main subject of research. In contrast, limited information is available on the mechanisms that allow the bacterium to accommodate...