Michael Konopka
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Explore the profile of Michael Konopka including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
126
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Recent Articles
1.
Singh S, Lamichhane A, Rafsanjani Nejad P, Heiss J, Baumann H, Gudneppanavar R, et al.
Mol Cancer Res
. 2022 Mar;
20(7):1166-1177.
PMID: 35348758
Implications: Leveraging a state-of-the-art organotypic tumor model, we demonstrated that CAFs-mediated HGF-MET signaling drive tumorigenic activities in TNBC and presents a therapeutic target.
2.
Dahal D, Pokhrel S, McDonald L, Bertman K, Paruchuri S, Konopka M, et al.
ACS Appl Bio Mater
. 2022 Jan;
2(9):4037-4043.
PMID: 35021337
Lysosome imaging without perturbing intracellular activity remains challenging, as the current commercial lysosome probes contain weakly basic amino groups that could perturb lysosome pH. Herein, we illustrate NIR-emitting dyes 2...
3.
Lazic M, Gudneppanavar R, Whiddon K, Sauvageau D, Stein L, Konopka M
Appl Microbiol Biotechnol
. 2021 Dec;
106(2):811-819.
PMID: 34921330
Methane is a common industrial by-product that can be used as feedstock for production of the biopolymer polyhydroxybutyrate (PHB) by alphaproteobacterial methanotrophs. In vivo assessment of PHB production would shed...
4.
Pukale D, Farrag M, Gudneppanavar R, Baumann H, Konopka M, Shriver L, et al.
ACS Chem Neurosci
. 2021 Sep;
12(19):3567-3578.
PMID: 34550670
Syringomyelia (SM) is primarily characterized by the formation of a fluid-filled cyst that forms in the parenchyma of the spinal cord following injury or other pathology. Recent omics studies in...
5.
Dahal D, Ojha K, Pokhrel S, Paruchuri S, Konopka M, Liu Q, et al.
Dyes Pigm
. 2021 Aug;
194.
PMID: 34366501
Near-infrared (NIR) emitting probes with very large Stokes' shifts play a crucial role in bioimaging applications, as the optical signals in this region exhibit high signal to background ratio and...
6.
Bertman K, Abeywickrama C, Baumann H, Alexander N, McDonald L, Shriver L, et al.
J Mater Chem B
. 2020 Apr;
6(31):5050-5058.
PMID: 32254534
Lysosomes are vital organelles in living cells, which have acidic environments (pH 4.0-5.0) where macrobiomolecules and malfunctioning organelles are broken down into monomers by hydrolase activity. The majority of the...
7.
Abeywickrama C, Bertman K, Mcdonald L, Alexander N, Dahal D, Baumann H, et al.
J Mater Chem B
. 2019 Nov;
7(47):7502-7514.
PMID: 31712794
HBT-Cy 1 has been previously reported as a highly selective fluorescent probe for lysosome visualization in live cells. To further investigate the role of the structural components of HBT-Cy in...
8.
Dahal D, McDonald L, Pokhrel S, Paruchuri S, Konopka M, Pang Y
Chem Commun (Camb)
. 2019 Oct;
55(88):13223-13226.
PMID: 31595909
There are a limited number of near-infrared (NIR) emitting (λem = 700-900 nm) molecular probes for imaging applications. A NIR-emitting probe that exhibits emission at ∼800 nm with a large...
9.
McDonald L, Dahal D, Konopka M, Liu Q, Pang Y
Bioorg Chem
. 2019 Jun;
89:103040.
PMID: 31195328
Hearing loss is a significant public health problem, and the "loss of sensory hair cells" is one of two leading causes in humans. Advanced imaging reagents are desirable for understanding...
10.
Bertman K, Abeywickrama C, Ingle A, Shriver L, Konopka M, Pang Y
J Fluoresc
. 2019 Apr;
29(3):599-607.
PMID: 30955153
Lysosome selective bright orange-red emitting flavonoid (2) was synthesized by attaching a strong donor (NPh) group into flavonoid skeleton. As a result of efficient intra molecular charge transfer due to...