Leah P Shriver
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Explore the profile of Leah P Shriver including associated specialties, affiliations and a list of published articles.
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61
Citations
1580
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Recent Articles
1.
Akbary Moghaddam V, Acharya S, Schwaiger-Haber M, Liao S, Jung W, Thyagarajan B, et al.
bioRxiv
. 2025 Feb;
PMID: 39896668
Small molecules (SMs) are integral to biological processes, influencing metabolism, homeostasis, and regulatory networks. Despite their importance, a significant knowledge gap exists regarding their downstream effects on biological pathways and...
2.
Kung C, Terzich N, Ilagen M, Prinsen M, Kaushal M, Kladney R, et al.
bioRxiv
. 2025 Feb;
PMID: 39896528
Triple-negative breast cancer (TNBC), lacking expression of estrogen, progesterone, and HER2 receptors, is aggressive and lacks targeted treatment options. An RNA editing enzyme, adenosine deaminase acting on RNA 1 (ADAR1),...
3.
Pan Y, Sindelar M, Stancliffe E, Shriver L, Middleton R, Patti G
Animals (Basel)
. 2025 Jan;
14(24.
PMID: 39765481
In dogs, brain aging may lead to cognitive decline and cognitive dysfunction syndrome (CDS) [...].
4.
Bandyopadhyay D, Tran E, Patel R, Luetzen M, Cho K, Shriver L, et al.
Cell Commun Signal
. 2024 Dec;
22(1):597.
PMID: 39696286
One of the hallmarks of cancer is metabolic reprogramming which controls cellular homeostasis and therapy resistance. Here, we investigated the effect of momordicine-I (M-I), a key bioactive compound from Momordica...
5.
Fowle-Grider R, Rowles 3rd J, Shen I, Wang Y, Schwaiger-Haber M, Dunham A, et al.
Nature
. 2024 Dec;
636(8043):737-744.
PMID: 39633044
Fructose consumption has increased considerably over the past five decades, largely due to the widespread use of high-fructose corn syrup as a sweetener. It has been proposed that fructose promotes...
6.
Tiwari A, Myeong J, Hashemiaghdam A, Stunault M, Zhang H, Niu X, et al.
Sci Adv
. 2024 Nov;
10(46):eadp7423.
PMID: 39546604
Glucose has long been considered the primary fuel source for the brain. However, glucose levels fluctuate in the brain during sleep or circuit activity, posing major metabolic stress. Here, we...
7.
Sun J, Zhang Y, Adams J, Higgins C, Kelly S, Zhang H, et al.
Cell Rep
. 2024 Oct;
43(10):114865.
PMID: 39412985
Organisms integrate circadian and metabolic signals to optimize substrate selection to survive starvation, yet precisely how this occurs is unclear. Here, we show that hepatocyte Period 1 (Per1) is selectively...
8.
Zhang Y, Higgins C, Tica S, Adams J, Sun J, Kelly S, et al.
Cell Metab
. 2024 Aug;
36(9):2069-2085.e8.
PMID: 39116884
Urea cycle impairment and its relationship to obesity and inflammation remained elusive, partly due to the dramatic clinical presentation of classical urea cycle defects. We generated mice with hepatocyte-specific arginase...
9.
Abri S, Durr H, Barton H, Adkins-Travis K, Shriver L, Pukale D, et al.
Biomater Sci
. 2024 Jun;
12(13):3458-3470.
PMID: 38836321
Current treatment strategies for infection of chronic wounds often result in compromised healing and necrosis due to antibiotic toxicity, and underlying biomarkers affected by treatments are not fully known. Here,...
10.
Kohler J, Legro N, Baldridge D, Shin J, Bowman A, Ugur B, et al.
Genet Med
. 2024 May;
26(9):101166.
PMID: 38767059
Purpose: The function of FAM177A1 and its relationship to human disease is largely unknown. Recent studies have demonstrated FAM177A1 to be a critical immune-associated gene. One previous case study has...