Michael Kahn
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Explore the profile of Michael Kahn including associated specialties, affiliations and a list of published articles.
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132
Citations
6322
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Recent Articles
21.
p300 Serine 89: A Critical Signaling Integrator and Its Effects on Intestinal Homeostasis and Repair
Lai K, Hu X, Chosa K, Nguyen C, Lin D, Lai K, et al.
Cancers (Basel)
. 2021 Apr;
13(6).
PMID: 33799418
Differential usage of Kat3 coactivators, CBP and p300, by β-catenin is a fundamental regulatory mechanism in stem cell maintenance and initiation of differentiation and repair. Based upon our earlier pharmacologic...
22.
Nagaraj A, Knarr M, Sekhar S, Connor R, Joseph P, Kovalenko O, et al.
Cancer Res
. 2021 Feb;
81(8):2044-2055.
PMID: 33574092
Wnt signaling is a major driver of stemness and chemoresistance in ovarian cancer, yet the genetic drivers that stimulate its expression remain largely unknown. Unlike other cancers, mutations in the...
23.
Skell J, Kahn M, Foxman B
Acta Crystallogr C Struct Chem
. 2021 Feb;
77(Pt 2):84-89.
PMID: 33536371
While Δ-tetrahydrocannabinolic acid A (THCA-A) has been reported to be difficult to crystallize and/or amorphous, we have obtained THCA-A in a pure crystalline form by extraction of marijuana and selective...
24.
Wild-type APC Is Associated with Poor Survival in Metastatic Microsatellite Stable Colorectal Cancer
Wang C, Ouyang C, Cho M, Ji J, Sandhu J, Goel A, et al.
Oncologist
. 2020 Nov;
26(3):208-214.
PMID: 33230914
Background: The prognostic implication of wild-type APC (APC-WT) in microsatellite stable (MSS) metastatic colorectal cancer (mCRC) is not well defined. Materials And Methods: APC prognostic value was evaluated retrospectively in...
25.
Chi F, Liu J, Brady S, Cosgrove P, Nath A, McQuerry J, et al.
Transl Oncol
. 2020 Nov;
14(1):100946.
PMID: 33221681
Cancer cell phenotypes evolve during a tumor's treatment. In some cases, tumor cells acquire cancer stem cell-like (CSL) traits such as resistance to chemotherapy and diminished differentiation; therefore, targeting these...
26.
Slepian P, Peng M, Janmohamed T, Kotteeswaran Y, Manoo V, Blades A, et al.
Digit Health
. 2020 Oct;
6:2055207620962297.
PMID: 33117557
Objective: Mobile health platforms have become an important component of pain self-management programs and hundreds of mobile applications are commercially available for patients to monitor pain. However, few of these...
27.
Chan L, Lung H, Ngan R, Lee A, Tsao S, Lo K, et al.
Int J Mol Sci
. 2020 Aug;
21(15).
PMID: 32752071
The Wnt signaling pathway is one of the major signaling pathways used by cancer stem cells (CSC). Ecotropic Viral Integration Site 1 (EVI1) has recently been shown to regulate oncogenic...
28.
Bild A, Teo J, Kahn M
Cancer Drug Resist
. 2020 May;
2:917-932.
PMID: 32426696
Cancers are heterogeneous at the cellular level. Cancer stem cells/tumor initiating cells (CSC/TIC) both initiate tumorigenesis and are responsible for therapeutic resistance and disease relapse. Elimination of CSC/TIC should therefore...
29.
Shuck S, Nguyen C, Chan Y, OConnor T, Ciminera A, Kahn M, et al.
Anal Chem
. 2020 May;
92(11):7556-7564.
PMID: 32366088
Understanding the complex relationships between genomics, transcriptomics, and proteomics requires the development of more sensitive and rapid methods of multiplexed protein analysis. This is necessary to understand the relationship between...
30.
Lukaszewicz A, Nguyen C, Melendez E, Lin D, Teo J, Lai K, et al.
Cancers (Basel)
. 2019 Jul;
11(7).
PMID: 31324005
Normal long-term repopulating somatic stem cells (SSCs) preferentially divide asymmetrically, with one daughter cell remaining in the niche and the other going on to be a transient amplifying cell required...