Michael McMillan
Overview
Explore the profile of Michael McMillan including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
424
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Recent Articles
1.
McMillan M, Gomez N, Hsieh C, Bekier M, Li X, Miguez R, et al.
Mol Cell
. 2023 Jan;
83(2):219-236.e7.
PMID: 36634675
RNA methylation at adenosine N6 (m6A) is one of the most common RNA modifications, impacting RNA stability, transport, and translation. Previous studies uncovered RNA destabilization in amyotrophic lateral sclerosis (ALS)...
2.
Higuchi Y, Nguyen C, Yasuda S, McMillan M, Hasegawa K, Kahn M
Curr Mol Pharmacol
. 2015 May;
9(3):272-279.
PMID: 26008738
Despite their high degree of identity and even higher homology, the two Kat3 transcriptional coactivators, CBP and p300, have distinct functions, particularly within the Wnt/β-catenin signaling cascade. ICG-001, by directly...
3.
Hasegawa K, Yasuda S, Teo J, Nguyen C, McMillan M, Hsieh C, et al.
Stem Cells Transl Med
. 2012 Dec;
1(1):18-28.
PMID: 23197636
An optimal culture system for human pluripotent stem cells should be fully defined and free of animal components. To date, most xeno-free culture systems require human feeder cells and/or highly...
4.
Milosevic J, Pandit K, Magister M, Rabinovich E, Ellwanger D, Yu G, et al.
Am J Respir Cell Mol Biol
. 2012 Oct;
47(6):879-87.
PMID: 23043088
In this study, we explored the regulation and the role of up-regulated microRNAs in idiopathic pulmonary fibrosis (IPF), a progressive interstitial lung disease of unknown origin. We analyzed the expression...
5.
Wang Z, Watt W, Brooks N, Harris M, Urban J, Boatman D, et al.
Biochim Biophys Acta
. 2010 Jun;
1804(9):1817-31.
PMID: 20580860
Because of their central role in programmed cell death, the caspases are attractive targets for developing new therapeutics against cancer and autoimmunity, myocardial infarction and ischemic damage, and neurodegenerative diseases....
6.
Miyabayashi T, Teo J, Yamamoto M, McMillan M, Nguyen C, Kahn M
Proc Natl Acad Sci U S A
. 2007 Mar;
104(13):5668-73.
PMID: 17372190
Embryonic stem cells (ESCs) represent an important research tool and a potential resource for regenerative medicine. Generally, ESCs are cocultured with a supportive feeder cell layer of murine embryonic fibroblasts,...
7.
McMillan M, Kahn M
Drug Discov Today
. 2005 Oct;
10(21):1467-74.
PMID: 16243267
Chemical genomics is a powerful method to complement more traditional genetic techniques (i.e. knockout mice, siRNA) for the dissection of complex signaling networks. Wnt signaling in mammals is a complex...
8.
Souza D, Vieira A, Pinho V, Sousa L, Andrade A, Bonjardim C, et al.
Br J Pharmacol
. 2005 Mar;
145(2):246-54.
PMID: 15765103
1 The nuclear translocation of transcription factors may be a critical factor in the intracellular pathway involved in ischaemia/reperfusion (I/R) injury. Here, we examined whether NF-kappaB and AP-1 participated in...
9.
Eguchi M, McMillan M, Nguyen C, Teo J, Chi E, Henderson Jr W, et al.
Comb Chem High Throughput Screen
. 2003 Dec;
6(7):611-21.
PMID: 14683490
There is increasing evidence that redox regulation of transcription, particularly activator protein-1 (AP-1) and nuclear factor kappa B (NF-kappaB), is important in inflammatory diseases. Human thioredoxin (TRX), a member of...