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Michael Kahn

Explore the profile of Michael Kahn including associated specialties, affiliations and a list of published articles. Areas
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Articles 132
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Recent Articles
11.
Shen Y, Chen Y, Lin Y, Li Y, Liu P, Zhang B, et al.
Cell Death Dis . 2023 Feb; 14(2):107. PMID: 36774351
In oral squamous cell carcinoma (OSCC), a highly aggressive and frequently lethal malignancy, the role and action mechanism of the microtubule regulatory protein CDK5RAP2 have not been fully understood. Here,...
12.
Kahn M
Cancers (Basel) . 2023 Jan; 15(2). PMID: 36672293
A deeper understanding of the biology of therapy resistance is important for the development of optimal strategies to attain complete cancer cures [...].
13.
Yu H, Kleiman V, Kojic K, Slepian P, Cortes H, McRae K, et al.
Transplantation . 2022 Dec; 107(6):1398-1405. PMID: 36482750
Background: With >700 transplant surgeries performed each year, Toronto General Hospital (TGH) is currently one of the largest adult transplant centers in North America. There is a lack of literature...
14.
Chen L, Chiang Y, Chan L, Chau W, Lung M, Kahn M, et al.
Cancers (Basel) . 2022 Jul; 14(13). PMID: 35804897
Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-associated malignancy ranking as the 23rd most common cancer globally, while its incidence rate ranked the 9th in southeast Asia. Tumor metastasis is...
15.
Wong A, Ding X, Wong A, Xu M, Zhang L, Leung H, et al.
J Hepatol . 2022 Mar; 77(2):410-423. PMID: 35351523
Background & Aims: The hepatic manifestation of the metabolic syndrome, non-alcoholic fatty liver disease (NAFLD), can lead to the development of hepatocellular carcinoma (HCC). Despite a strong causative link, NAFLD-HCC...
16.
Hu X, Ono M, Chimge N, Chosa K, Nguyen C, Melendez E, et al.
Cancers (Basel) . 2021 Dec; 13(23). PMID: 34884992
The integration of cellular status with metabolism is critically important and the coupling of energy production and cellular function is highly evolutionarily conserved. This has been demonstrated in stem cell...
17.
Kahn M
Expert Opin Ther Targets . 2021 Oct; 25(9):701-719. PMID: 34633266
Areas Covered: This perspective discusses the challenges of targeting the Wnt signaling cascade, the safety, efficacy, and therapeutic potential of specific CBP/β-catenin antagonists and a rationale for the pleiotropic effects...
18.
Pfaff E, Girvin A, Gabriel D, Kostka K, Morris M, Palchuk M, et al.
J Am Med Inform Assoc . 2021 Sep; 29(4):609-618. PMID: 34590684
Objective: In response to COVID-19, the informatics community united to aggregate as much clinical data as possible to characterize this new disease and reduce its impact through collaborative analytics. The...
19.
Lai K, Kahn M
Handb Exp Pharmacol . 2021 Aug; 269:383-422. PMID: 34463849
WNT/β-catenin signaling plays fundamental roles in numerous developmental processes and in adult tissue homeostasis and repair after injury, by controlling cellular self-renewal, activation, division, differentiation, movement, genetic stability, and apoptosis....
20.
Liu C, Page M, Weinrib A, Wong D, Huang A, McRae K, et al.
J Anesth . 2021 May; 35(4):505-514. PMID: 34002257
Purpose: Chronic post-surgical pain (CPSP) is a highly prevalent complication following thoracic surgery. This is a prospective cohort study that aims to describe the pain trajectories of patients undergoing thoracic...