Michael J Ziller
Overview
Explore the profile of Michael J Ziller including associated specialties, affiliations and a list of published articles.
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41
Citations
6425
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Recent Articles
1.
Gerstner N, Frohlich A, Matosin N, Gagliardi M, Cruceanu C, Kodel M, et al.
Sci Adv
. 2025 Mar;
11(10):eadq2290.
PMID: 40053590
Psychiatric disorders like schizophrenia, bipolar disorder, and major depressive disorder exhibit substantial genetic and clinical overlap. However, their molecular architecture remains elusive due to their polygenic nature and complex brain...
2.
Boudriot E, Stephan M, Rabe F, Smigielski L, Schmitt A, Falkai P, et al.
JAMA Psychiatry
. 2025 Jan;
82(3):285-295.
PMID: 39775833
Importance: As an accessible part of the central nervous system, the retina provides a unique window to study pathophysiological mechanisms of brain disorders in humans. Imaging and electrophysiological studies have...
3.
Frohlich A, Gerstner N, Gagliardi M, Kodel M, Yusupov N, Matosin N, et al.
Nat Neurosci
. 2024 Sep;
27(10):2021-2032.
PMID: 39227716
Aging is a complex biological process and represents the largest risk factor for neurodegenerative disorders. The risk for neurodegenerative disorders is also increased in individuals with psychiatric disorders. Here, we...
4.
Distinct genetic liability profiles define clinically relevant patient strata across common diseases
Trastulla L, Dolgalev G, Moser S, Jimenez-Barron L, Andlauer T, von Scheidt M, et al.
Nat Commun
. 2024 Jul;
15(1):5534.
PMID: 38951512
Stratified medicine holds great promise to tailor treatment to the needs of individual patients. While genetics holds great potential to aid patient stratification, it remains a major challenge to operationalize...
5.
Raabe F, Hausruckinger A, Gagliardi M, Ahmad R, Almeida V, Galinski S, et al.
bioRxiv
. 2024 Jan;
PMID: 38260577
Schizophrenia (SCZ) is a genetically heterogenous psychiatric disorder of highly polygenic nature. Correlative evidence from genetic studies indicate that the aggregated effects of distinct genetic risk factor combinations found in...
6.
Rummel C, Gagliardi M, Ahmad R, Herholt A, Jimenez-Barron L, Murek V, et al.
Cell
. 2023 Oct;
186(23):5165-5182.e33.
PMID: 37852259
Schizophrenia (SCZ) is a highly heritable mental disorder with thousands of associated genetic variants located mostly in the noncoding space of the genome. Translating these associations into insights regarding the...
7.
Kearns N, Lobo M, Genga R, Abramowitz R, Parsi K, Min J, et al.
Dev Cell
. 2023 Sep;
58(18):1801-1818.e15.
PMID: 37751684
Approaches to study human pharyngeal foregut endoderm-a developmental intermediate that is linked to various human syndromes involving pharynx development and organogenesis of tissues such as thymus, parathyroid, and thyroid-have been...
8.
Rummel C, Gagliardi M, Herholt A, Ahmad R, Murek V, Weigert L, et al.
bioRxiv
. 2023 Jul;
PMID: 37425902
Schizophrenia (SCZ) is a highly polygenic disease and genome wide association studies have identified thousands of genetic variants that are statistically associated with this psychiatric disorder. However, our ability to...
9.
Distinct genetic liability profiles define clinically relevant patient strata across common diseases
Trastulla L, Moser S, Jimenez-Barron L, Andlauer T, von Scheidt M, Budde M, et al.
medRxiv
. 2023 May;
PMID: 37214898
Genome-wide association studies have unearthed a wealth of genetic associations across many complex diseases. However, translating these associations into biological mechanisms contributing to disease etiology and heterogeneity has been challenging....
10.
Matosin N, Arloth J, Czamara D, Edmond K, Maitra M, Frohlich A, et al.
Acta Neuropathol
. 2023 Feb;
145(4):439-459.
PMID: 36729133
Identification and characterisation of novel targets for treatment is a priority in the field of psychiatry. FKBP5 is a gene with decades of evidence suggesting its pathogenic role in a...