Michael J Raher
Overview
Explore the profile of Michael J Raher including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
968
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0
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Recent Articles
1.
Dordea A, Vandenwijngaert S, Garcia V, Tainsh R, Nathan D, Allen K, et al.
Am J Physiol Heart Circ Physiol
. 2016 May;
310(11):H1790-800.
PMID: 27199131
Dysregulated nitric oxide (NO) signaling contributes to the pathogenesis of hypertension, a prevalent and often sex-specific risk factor for cardiovascular disease. We previously reported that mice deficient in the α1-subunit...
2.
Clerte M, Baron D, Brouckaert P, Ernande L, Raher M, Flynn A, et al.
J Am Soc Echocardiogr
. 2013 Sep;
26(12):1465-73.
PMID: 23993691
Background: When activated by the sympathetic nervous system, brown adipose tissue (BAT) increases energy expenditure to produce heat. Augmenting BAT mass or increasing BAT activation could potentially be used to...
3.
Baron D, Clerte M, Brouckaert P, Raher M, Flynn A, Zhang H, et al.
Circ Cardiovasc Imaging
. 2012 Jul;
5(5):652-9.
PMID: 22776888
Background: Interventions to increase brown adipose tissue (BAT) volume and activation are being extensively investigated as therapies to decrease the body weight in obese subjects. Noninvasive methods to monitor these...
4.
Buys E, Raher M, Kirby A, Shahid M, Mohd S, Baron D, et al.
J Clin Invest
. 2012 May;
122(6):2316-25.
PMID: 22565307
Nitric oxide (NO) plays an essential role in regulating hypertension and blood flow by inducing relaxation of vascular smooth muscle. Male mice deficient in a NO receptor component, the α1...
5.
Kurtz B, Thibault H, Raher M, Popovich J, Cawley S, Atochin D, et al.
Am J Physiol Heart Circ Physiol
. 2011 Aug;
301(5):H2093-101.
PMID: 21856905
Insulin resistance (IR) and systemic hypertension are independently associated with heart failure. We reported previously that nitric oxide synthase 3 (NOS3) has a beneficial effect on left ventricular (LV) remodeling...
6.
Tournoux F, Petersen B, Thibault H, Zou L, Raher M, Kurtz B, et al.
J Am Soc Echocardiogr
. 2011 Feb;
24(4):465-70.
PMID: 21315557
Background: Although multiple echocardiographic methods exist to calculate cardiac output (CO), they have not been validated in mice using a reference method. Methods: Echocardiographic and flow probe measurements of CO...
7.
Weng M, Raher M, Leyton P, Combs T, Scherer P, Bloch K, et al.
Am J Respir Cell Mol Biol
. 2010 Nov;
45(2):340-7.
PMID: 21075862
Remodeling of the pulmonary arteries is a common feature among the heterogeneous disorders that cause pulmonary hypertension. In these disorders, the remodeled pulmonary arteries often demonstrate inflammation and an accumulation...
8.
Yu B, Shahid M, Egorina E, Sovershaev M, Raher M, Lei C, et al.
Anesthesiology
. 2010 Feb;
112(3):586-94.
PMID: 20179495
Background: To date, there is no safe and effective hemoglobin-based oxygen carrier (HBOC) to substitute for erythrocyte transfusion. It is uncertain whether a deficiency of endothelial nitric oxide bioavailability (endothelial...
9.
Thibault H, Kurtz B, Raher M, Shaik R, Waxman A, Derumeaux G, et al.
Circ Cardiovasc Imaging
. 2010 Jan;
3(2):157-63.
PMID: 20044514
Background: Genetically modified mice offer the unique opportunity to gain insight into the pathophysiology of pulmonary arterial hypertension. In mice, right heart catheterization is the only available technique to measure...
10.
Derumeaux G, Ichinose F, Raher M, Morgan J, Coman T, Lee C, et al.
Circ Cardiovasc Imaging
. 2009 Oct;
1(3):227-34.
PMID: 19808547
Background: Aging is accompanied by an alteration in myocardial contractility. However, its noninvasive detection is difficult. The effect of chronic exercise on this decrease is unknown. Murine models of senescence...