Michael J Owens
Overview
Explore the profile of Michael J Owens including associated specialties, affiliations and a list of published articles.
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Articles
93
Citations
1802
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Recent Articles
1.
Thrivikraman K, Kinkead B, Owens M, Rapaport M, Plotsky P
Neuroendocrinology
. 2021 Oct;
112(8):763-776.
PMID: 34649254
Introduction: Activation of the locus coeruleus-noradrenergic (LC-NA) system during awakening is associated with an increase in plasma corticosterone and cardiovascular tone. These studies evaluate the role of the LC in...
2.
Stehouwer J, Birnbaum M, Voll R, Owens M, Plott S, Bourke C, et al.
Bioorg Med Chem
. 2020 Aug;
28(19):115660.
PMID: 32747078
No abstract available.
3.
Coplan J, Lu D, El Sehamy A, Tang C, Jackowski A, Abdallah C, et al.
Chronic Stress (Thousand Oaks)
. 2018 Jul;
2.
PMID: 29963652
Introduction: Using proton magnetic resonance spectroscopy imaging (H-MRSI), the effects of early life stress (ELS) on nonhuman primate striatal neuronal integrity were examined as reflected by -acetyl aspartate (NAA) concentrations....
4.
Coplan J, Rozenboym A, Fulton S, Panthangi V, Tang J, Thiramangalakdi L, et al.
Neurobiol Stress
. 2018 Jun;
8:202-210.
PMID: 29888314
Background: Early life stress (ELS) in macaques in the form of insecure maternal attachment putatively induces epigenetic adaptations resulting in a "thrifty phenotype" throughout the life cycle. For instance, ELS...
5.
Adhikarla V, Dunlop B, Jarkas N, Goodman M, Mayberg H, Owens M, et al.
J Nucl Med
. 2017 Sep;
59(2):315-319.
PMID: 28935840
The aim of this study was to measure the test-retest reliability of C--dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)benzylamine (C-HOMADAM) imaging of serotonin transporter (SERT) density in healthy control subjects. Two female and 2 male volunteers...
6.
Syed S, Smith E, Batuman O, Rosenblum L, Owens M, Nemeroff C, et al.
Neurosci Lett
. 2017 Mar;
647:20-25.
PMID: 28330718
Introduction: Early life stress (ELS) has been shown to play a role in establishing persistent maladaptive HPA axis modifications that may contribute to the pathogenesis of mood and anxiety disorders....
7.
Neigh G, Nemeth C, Kelly S, Hardy E, Bourke C, Stowe Z, et al.
Physiol Behav
. 2016 Jul;
172:24-30.
PMID: 27422674
Prenatal stress has been linked to deficits in neurological function including deficient social behavior, alterations in learning and memory, impaired stress regulation, and susceptibility to adult disease. In addition, prenatal...
8.
Murray K, Ressler K, Owens M
Pharmacol Biochem Behav
. 2015 Dec;
141:50-7.
PMID: 26621784
Escitalopram is a commonly prescribed antidepressant of the selective serotonin reuptake inhibitor class. Clinical evidence and mapping of the serotonin transporter (SERT) identified that escitalopram, in addition to its binding...
9.
Stehouwer J, Bourke C, Owens M, Voll R, Kilts C, Goodman M
Bioorg Med Chem Lett
. 2015 Oct;
25(22):5111-4.
PMID: 26456805
Compounds 1-14 were synthesized in a search for high-affinity CRF1 receptor ligands that could be radiolabeled with (11)C or (18)F for use as positron emission tomography (PET) radiotracers. Derivatives of...
10.
Stehouwer J, Birnbaum M, Voll R, Owens M, Plott S, Bourke C, et al.
Bioorg Med Chem
. 2015 Jul;
23(15):4286-4302.
PMID: 26145817
A series of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines were synthesized and evaluated as potential positron emission tomography (PET) tracers for the corticotropin-releasing factor type-1 (CRF1) receptor. Compounds 27, 28, 29, and 30 all displayed...