Michael J Carrozza
Overview
Explore the profile of Michael J Carrozza including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
1611
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Recent Articles
1.
2.
Breimann L, Morao A, Kim J, Sebastian Jimenez D, Maryn N, Bikkasani K, et al.
J Cell Sci
. 2021 Dec;
135(2).
PMID: 34918745
Condensin is a multi-subunit structural maintenance of chromosomes (SMC) complex that binds to and compacts chromosomes. Here, we addressed the regulation of condensin binding dynamics using Caenorhabditis elegans condensin DC,...
3.
Chittuluru J, Chaban Y, Monnet-Saksouk J, Carrozza M, Sapountzi V, Selleck W, et al.
Nat Struct Mol Biol
. 2011 Oct;
18(11):1196-203.
PMID: 21984211
We have used EM and biochemistry to characterize the structure of NuA4, an essential yeast histone acetyltransferase (HAT) complex conserved throughout eukaryotes, and we have determined the interaction of NuA4...
4.
Horton J, Stefanick D, Zeng J, Carrozza M, Wilson S
DNA Repair (Amst)
. 2010 Dec;
10(2):225-34.
PMID: 21130714
Treatment of PARP-1-expressing cells with the combination of a DNA methylating agent (MMS) and the PARP inhibitor 4-amino-1,8-naphthalimide (4-AN) leads to an ATR/Chk1-dependent S phase checkpoint and cell death by...
5.
Wilson S, Beard W, Shock D, Batra V, Cavanaugh N, Prasad R, et al.
Cell Mol Life Sci
. 2010 Sep;
67(21):3633-47.
PMID: 20844920
Base excision repair (BER) can protect a cell after endogenous or exogenous genotoxic stress, and a deficiency in BER can render a cell hypersensitive to stress-induced apoptotic and necrotic cell...
6.
Sardiu M, Gilmore J, Carrozza M, Li B, Workman J, Florens L, et al.
PLoS One
. 2009 Oct;
4(10):e7310.
PMID: 19806189
Protein complexes are key molecular machines executing a variety of essential cellular processes. Despite the availability of genome-wide protein-protein interaction studies, determining the connectivity between proteins within a complex remains...
7.
Carrozza M, Stefanick D, Horton J, Kedar P, Wilson S
DNA Repair (Amst)
. 2009 Sep;
8(11):1264-72.
PMID: 19717351
By limiting cell cycle progression following detection of DNA damage, checkpoints are critical for cell survival and genome stability. Methylated DNA damage, when combined with inhibition of PARP activity, results...
8.
Gutierrez J, Chandy M, Carrozza M, Workman J
EMBO J
. 2007 Jan;
26(3):730-40.
PMID: 17235287
ATP-dependent chromatin remodeling complexes play a critical role in chromatin dynamics. A large number of in vitro studies have pointed towards nucleosome sliding as the principal remodeling outcome of SWI/SNF...
9.
Carrozza M, Florens L, Swanson S, Shia W, Anderson S, Yates J, et al.
Biochim Biophys Acta
. 2005 Nov;
1731(2):77-87.
PMID: 16314178
Histone deacetylation by Saccharomyces cerevisiae Rpd3 represses genes regulated by the Ash1 and Ume6 DNA-binding proteins. Rpd3 exists in a small 0.6 MDa (Rpd3S) and large 1.2 MDa (Rpd3L) corepressor...
10.
Carrozza M, Li B, Florens L, Suganuma T, Swanson S, Lee K, et al.
Cell
. 2005 Nov;
123(4):581-92.
PMID: 16286007
Yeast Rpd3 histone deacetylase plays an important role at actively transcribed genes. We characterized two distinct Rpd3 complexes, Rpd3L and Rpd3S, by MudPIT analysis. Both complexes shared a three subunit...