Michael Gleimer
Overview
Explore the profile of Michael Gleimer including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
979
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Recent Articles
1.
Goyos A, Guethlein L, Horowitz A, Hilton H, Gleimer M, Brodsky F, et al.
J Immunol
. 2015 Sep;
195(8):3725-36.
PMID: 26371256
Chimpanzees have orthologs of the six fixed, functional human MHC class I genes. But, in addition, the chimpanzee has a seventh functional gene, Patr-AL, which is not polymorphic but contributes...
2.
Gleimer M, von Boehmer H, Kreslavsky T
Front Immunol
. 2012 Dec;
3:374.
PMID: 23267359
Natural killer (NKT) T cells exhibit tissue distribution, surface phenotype, and functional responses that are strikingly different from those of conventional T cells. The transcription factor PLZF is responsible for...
3.
Kreslavsky T, Gleimer M, Miyazaki M, Choi Y, Gagnon E, Murre C, et al.
Immunity
. 2012 Nov;
37(5):840-53.
PMID: 23159226
Proliferation and differentiation are tightly coordinated to produce an appropriate number of differentiated cells and often exhibit an antagonistic relationship. Developing T cells, which arise in the thymus from a...
4.
Gleimer M, Wahl A, Hickman H, Abi-Rached L, Norman P, Guethlein L, et al.
J Immunol
. 2011 Jan;
186(3):1575-88.
PMID: 21209280
Patr-AL is an expressed, non-polymorphic MHC class I gene carried by ∼50% of chimpanzee MHC haplotypes. Comparing Patr-AL(+) and Patr-AL(-) haplotypes showed Patr-AL defines a unique 125-kb genomic block flanked...
5.
Kreslavsky T, Gleimer M, Garbe A, von Boehmer H
Immunol Rev
. 2010 Oct;
238(1):169-81.
PMID: 20969592
Both αβ and γδ T cells develop in the thymus from a common progenitor. Historically distinguished by their T-cell receptor (TCR), these lineages are now defined on the basis of...
6.
Gleimer M, von Boehmer H
Curr Biol
. 2010 Apr;
20(7):R316-8.
PMID: 20392421
The development and function of lymphocytes depend upon their precise migration in response to chemoattractant cytokines, or chemokines. Two recent reports suggest that, during thymic beta-selection, the binding of the...
7.
Kreslavsky T, Gleimer M, von Boehmer H
Curr Opin Immunol
. 2010 Jan;
22(2):185-92.
PMID: 20074925
Alphabeta and gammadelta T cells develop in the thymus from a common precursor. Although lineages initially were defined by the type of TCR they express, it soon became clear that...
8.
Graef T, Moesta A, Norman P, Abi-Rached L, Vago L, Older Aguilar A, et al.
J Exp Med
. 2009 Oct;
206(11):2557-72.
PMID: 19858347
Human killer cell immunoglobulin-like receptors (KIRs) are distinguished by expansion of activating KIR2DS, whose ligands and functions remain poorly understood. The oldest, most prevalent KIR2DS is KIR2DS4, which is represented...
9.
Moesta A, Norman P, Yawata M, Yawata N, Gleimer M, Parham P
J Immunol
. 2008 Mar;
180(6):3969-79.
PMID: 18322206
Interactions between HLA-C ligands and inhibitory killer cell Ig-like receptors (KIR) control the development and response of human NK cells. This regulatory mechanism is usually described by mutually exclusive interactions...
10.
Norman P, Abi-Rached L, Gendzekhadze K, Korbel D, Gleimer M, Rowley D, et al.
Nat Genet
. 2007 Aug;
39(9):1092-9.
PMID: 17694054
Interactions of killer cell immunoglobulin-like receptors (KIRs) with major histocompatibility complex (MHC) class I ligands diversify natural killer cell responses to infection. By analyzing sequence variation in diverse human populations,...