Lisbeth A Guethlein
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Explore the profile of Lisbeth A Guethlein including associated specialties, affiliations and a list of published articles.
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96
Citations
4199
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Recent Articles
1.
Ross P, Hilton H, Lodwick J, Slezak T, Guethlein L, McMurtrey C, et al.
bioRxiv
. 2024 Dec;
PMID: 39651149
HLA class I alleles of archaic origin may have been retained in modern humans because they provide immunity against diseases to which archaic humans had evolved resistance. According to this...
2.
Loh L, Saunders P, Faoro C, Font-Porterias N, Nemat-Gorgani N, Harrison G, et al.
Cell
. 2024 Oct;
187(24):7008-7024.e19.
PMID: 39476840
Genetic variation in host immunity impacts the disproportionate burden of infectious diseases that can be experienced by First Nations peoples. Polymorphic human leukocyte antigen (HLA) class I and killer cell...
3.
Logsdon G, Ebert P, Audano P, Loftus M, Porubsky D, Ebler J, et al.
bioRxiv
. 2024 Oct;
PMID: 39372794
Diverse sets of complete human genomes are required to construct a pangenome reference and to understand the extent of complex structural variation. Here, we sequence 65 diverse human genomes and...
4.
Pollock N, Farias T, Kichula K, Sauter J, Scholz S, Nii-Trebi N, et al.
HLA
. 2024 Jun;
103(6):e15568.
PMID: 38923286
No abstract available.
5.
Mack S, Schefzyk D, Millius R, Maiers M, Hollenbach J, Pollack J, et al.
HLA
. 2023 Jun;
102(2):206-212.
PMID: 37286192
The Genotype List (GL) String grammar for reporting HLA and Killer-cell Immunoglobulin-like Receptor (KIR) genotypes in a text string was described in 2013. Since this initial description, GL Strings have...
6.
Cocker A, Guethlein L, Parham P
Biochem Soc Trans
. 2023 May;
51(3):1201-1212.
PMID: 37140380
Long-term human diseases can shape the immune system, and natural killer (NK) cells have been documented to differentiate into distinct subsets specifically associated with chronic virus infections. One of these...
7.
Houwaart T, Scholz S, Pollock N, Palmer W, Kichula K, Strelow D, et al.
HLA
. 2023 Mar;
102(1):28-43.
PMID: 36932816
Accurate and comprehensive immunogenetic reference panels are key to the successful implementation of population-scale immunogenomics. The 5Mbp Major Histocompatibility Complex (MHC) is the most polymorphic region of the human genome...
8.
Wroblewski E, Guethlein L, Anderson A, Liu W, Li Y, Heisel S, et al.
Nat Commun
. 2023 Feb;
14(1):1033.
PMID: 36823144
The malaria parasite Plasmodium falciparum causes substantial human mortality, primarily in equatorial Africa. Enriched in affected African populations, the B*53 variant of HLA-B, a cell surface protein that presents peptide...
9.
Cocker A, Liu F, Djaoud Z, Guethlein L, Parham P
Front Immunol
. 2022 Oct;
13:992723.
PMID: 36211403
Human NK cells are usually defined as CD3CD56 lymphocytes. However, a CD56CD16 (CD56neg) lymphocyte population that displays NK-associated markers expands during chronic viral infections such as HIV-1 and HCV, and,...
10.
Liu F, Cocker A, Pugh J, Djaoud Z, Parham P, Guethlein L
Immunogenetics
. 2022 May;
74(6):513-525.
PMID: 35562487
Leukocyte immunoglobulin-like receptor B1 (LILRB1) is widely expressed on various immune cells and the engagement of LILRB1 to HLA class I and pathogen-derived proteins can modulate the immune response. In...