Michael G Tordoff
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Explore the profile of Michael G Tordoff including associated specialties, affiliations and a list of published articles.
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72
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1786
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Recent Articles
1.
Flammer L, Ellis H, Rivers N, Caronia L, Ghidewon M, Christensen C, et al.
Br J Pharmacol
. 2024 May;
181(17):3282-3299.
PMID: 38745397
Background And Purpose: Many medications taste intensely bitter. The innate aversion to bitterness affects medical compliance, especially in children. There is a clear need to develop bitter blockers to suppress...
2.
Makhlouf M, Souza D, Kurian S, Bellaver B, Ellis H, Kuboki A, et al.
Mol Metab
. 2023 Nov;
79:101837.
PMID: 37977411
Objective: Food processing greatly contributed to increased food safety, diversity, and accessibility. However, the prevalence of highly palatable and highly processed food in our modern diet has exacerbated obesity rates...
3.
Bacharach S, Tordoff M, Alhadeff A
Cell Mol Gastroenterol Hepatol
. 2023 May;
16(2):189-199.
PMID: 37172823
The detection of nutrients in the gut influences ongoing and future feeding behavior as well as the development of food preferences. In addition to nutrient sensing in the intestine, the...
4.
Tordoff M, Ellis H
Physiol Behav
. 2021 Nov;
243:113644.
PMID: 34767835
To investigate the contributions of carbohydrate and fat to obesity we measured the body weight, body composition and food intake of adult C57BL/6J mice fed ad libitum with various combinations...
5.
Demi L, Taylor B, Reading B, Tordoff M, Dunn R
Ecol Evol
. 2021 Jul;
11(13):8441-8455.
PMID: 34257909
A major conceptual gap in taste biology is the lack of a general framework for understanding the evolution of different taste modalities among animal species. We turn to two complementary...
6.
Lin C, Inoue M, Li X, Bosak N, Ishiwatari Y, Tordoff M, et al.
Mamm Genome
. 2021 Mar;
32(2):51-69.
PMID: 33713179
Mice of the C57BL/6ByJ (B6) strain have higher consumption of sucrose, and stronger peripheral neural responses to it, than do mice of the 129P3/J (129) strain. To identify quantitative trait...
7.
Lin C, Tordoff M, Li X, Bosak N, Inoue M, Ishiwatari Y, et al.
Mamm Genome
. 2021 Mar;
32(2):70-93.
PMID: 33710367
We have previously used crosses between C57BL/6ByJ (B6) and 129P3/J (129) inbred strains to map a quantitative trait locus (QTL) on mouse chromosome (Chr) 4 that affects behavioral and neural...
8.
Ma Z, Taruno A, Ohmoto M, Jyotaki M, Lim J, Miyazaki H, et al.
Neuron
. 2018 Apr;
98(3):547-561.e10.
PMID: 29681531
Binding of sweet, umami, and bitter tastants to G protein-coupled receptors (GPCRs) in apical membranes of type II taste bud cells (TBCs) triggers action potentials that activate a voltage-gated nonselective...
9.
Workman A, Carey R, Chen B, Saunders C, Marambaud P, Mitchell C, et al.
Sci Rep
. 2017 Jul;
7(1):6687.
PMID: 28751666
Mechanical stimulation of airway epithelial cells causes apical release of ATP, which increases ciliary beat frequency (CBF) and speeds up mucociliary clearance. The mechanisms responsible for this ATP release are...
10.
Poole R, Tordoff M
J Caffeine Res
. 2017 Jun;
7(2):39-52.
PMID: 28660093
Many people avidly consume foods and drinks containing caffeine, despite its bitter taste. Here, we review what is known about caffeine as a bitter taste stimulus. Topics include caffeine's action...