Michael G Clark
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Explore the profile of Michael G Clark including associated specialties, affiliations and a list of published articles.
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1012
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Recent Articles
11.
Pacchia C, Kline G, Hamdan M, Clark K, Clark M, Smith M
Clin Auton Res
. 2011 May;
21(5):325-32.
PMID: 21553203
Background: Atrial fibrillation (AF) is the most common sustained dysrhythmia and appears to be an independent predictor of sudden cardiac death. The irregular ventricular rhythm contains both linear and non-linear...
12.
Bradley E, Eringa E, Stehouwer C, Korstjens I, van Nieuw Amerongen G, Musters R, et al.
Arterioscler Thromb Vasc Biol
. 2010 Mar;
30(6):1137-42.
PMID: 20224051
Objective: To investigate the effects of activation of the AMP-activated protein kinase (AMPK) on muscle perfusion and to elucidate the mechanisms involved. Methods And Results: In a combined approach, we...
13.
Newman J, Dwyer R, St-Pierre P, Richards S, Clark M, Rattigan S
J Physiol
. 2009 May;
587(Pt 11):2579-88.
PMID: 19403615
In addition to increased glucose uptake, insulin action is associated with increased total and microvascular blood flow, and vasomotion in skeletal muscle. The aim of this study was to determine...
14.
Yuen D, Dwyer R, Matthews V, Zhang L, Drew B, Neill B, et al.
Diabetes
. 2009 Feb;
58(5):1086-95.
PMID: 19188427
Objective: The cytokine interleukin-6 (IL-6) stimulates AMP-activated protein kinase (AMPK) and insulin signaling in skeletal muscle, both of which result in the activation of endothelial nitric oxide synthase (eNOS). We...
15.
Clark M
Am J Physiol Endocrinol Metab
. 2008 Jul;
295(4):E732-50.
PMID: 18612041
Insulin has an exercise-like action to increase microvascular perfusion of skeletal muscle and thereby enhance delivery of hormone and nutrient to the myocytes. With insulin resistance, insulin's action to increase...
16.
Rattigan S, Zhang L, Mahajan H, Kolka C, Richards S, Clark M
Curr Diabetes Rev
. 2008 Jan;
2(1):61-70.
PMID: 18220618
Insulin mediates its own access and that of glucose to muscle by capillary recruitment and an increase in bulk blood flow. In addition, insulin resistance of muscle may result in...
17.
Ross R, Downey K, Newman J, Richards S, Clark M, Rattigan S
Microvasc Res
. 2008 Jan;
75(3):323-9.
PMID: 18207201
Contrast-enhanced ultrasound (CEU) has been used to measure muscle microvascular perfusion in vivo in response to exercise and insulin. In the present study we address whether CEU measurement of capillary...
18.
Newman J, Ross R, Richards S, Clark M, Rattigan S
J Physiol
. 2007 Sep;
585(Pt 1):217-29.
PMID: 17884927
In the present study, a mathematical model using the microdialysis outflow: inflow (O/I) ratio of the novel analogue L-[14C]glucose has been developed which allows the calculation of the nutritive (and...
19.
Ross R, Wadley G, Clark M, Rattigan S, McConell G
Diabetes
. 2007 Sep;
56(12):2885-92.
PMID: 17881613
Objective: We have previously shown in humans that local infusion of a nitric oxide synthase (NOS) inhibitor into the femoral artery attenuates the increase in leg glucose uptake during exercise...
20.
Clark M, Rattigan S, Barrett E, Vincent M
J Appl Physiol (1985)
. 2007 Jul;
104(3):889-91.
PMID: 17656624
No abstract available.