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Michael Francis

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Articles 56
Citations 504
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Recent Articles
21.
Zhou J, Liu C, Francis M, Sun Y, Ryu M, Grider A, et al.
Nutrients . 2020 Oct; 12(10). PMID: 33080795
Blood levels of iron and copper, even within their normal ranges, have been associated with a wide range of clinical outcomes. The available epidemiological evidence for these associations is often...
22.
Kim M, Matheson L, Garrard B, Francis M, Broad A, Malone J, et al.
Aust J Rural Health . 2019 Apr; 27(2):183-187. PMID: 30945777
Problem: Optimal lung cancer care requires multidisciplinary team input, with access to specialised diagnostic and therapeutic services that may be limited in rural or regional areas and impact clinical outcomes....
23.
Francis M, Cheng H, Ma P, Grider A
Biol Trace Elem Res . 2019 Feb; 192(2):83-90. PMID: 30734197
The zinc transcriptional regulatory element (ZTRE) is a newly reported binding motif for human zinc finger protein ZNF658, which alters gene expression in response to cellular zinc. The ZTRE has...
24.
Francis M, Grider A
Biometals . 2018 Dec; 32(1):111-121. PMID: 30564968
Adequate zinc nutriture is necessary for normal bone growth and development, though the precise mechanisms for zinc-mediated bone growth remain poorly defined. A key transcription factor activated by zinc is...
25.
Conroy S, Francis M, Hulvershorn L
Curr Treat Options Psychiatry . 2018 Oct; 5(1):113-128. PMID: 30364516
Purpose Of Review: The goal of this paper is to review recent research on the identification and treatment of prodromal periods that precede bipolar and psychotic disorders. We also sought...
26.
Balczon R, Francis M, Leavesley S, Stevens T
J Vis Exp . 2018 Jul; (137). PMID: 30059033
Patients who survive pneumonia have elevated death rates in the months following hospital discharge. It has been hypothesized that infection of pulmonary tissue during pneumonia results in the production of...
27.
Francis M, Grider A
Biometals . 2018 May; 31(4):639-646. PMID: 29767398
The purpose of this study was to determine the correlation between the position or number of metal regulatory elements (MREs) near gene transcriptional or translational start sites, and the strength...
28.
Shen C, Romero M, Brunelle A, Wolfe C, Dobyns A, Francis M, et al.
Am J Physiol Regul Integr Comp Physiol . 2017 Nov; 314(3):R433-R446. PMID: 29167165
Long-term hypoxia (LTH) has a profound effect on pulmonary arterial vasoconstriction in the fetus and adult. Dysregulation in Ca signaling is important during the development of LTH-induced pulmonary hypertension. In...
29.
Francis M, Xu N, Zhou C, Stevens T
Am J Pathol . 2016 Apr; 186(6):1701-9. PMID: 27083517
The canonical transient receptor potential channel 4 (TRPC4) comprises an endothelial store-operated Ca(2+) entry channel, and TRPC4 inactivation confers a survival benefit in pulmonary arterial hypertension (PAH). Endothelial Ca(2+) signals...
30.
Francis M, Waldrup J, Qian X, Solodushko V, Meriwether J, Taylor M
Circ Res . 2016 Feb; 118(7):1078-90. PMID: 26838791
Rationale: Recent data from mesenteric and cerebral beds have revealed spatially restricted Ca(2+) transients occurring along the vascular intima that control effector recruitment and vasodilation. Although Ca(2+) is pivotal for...