Michael Fairhead
Overview
Explore the profile of Michael Fairhead including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
33
Citations
899
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
21.
Fairhead M, Veggiani G, Lever M, Yan J, Mesner D, Robinson C, et al.
J Am Chem Soc
. 2014 Aug;
136(35):12355-63.
PMID: 25111182
The capture of biotin by streptavidin is an inspiration for supramolecular chemistry and a central tool for biological chemistry and nanotechnology, because of the rapid and exceptionally stable interaction. However,...
22.
Fairhead M, Krndija D, Lowe E, Howarth M
J Mol Biol
. 2013 Sep;
426(1):199-214.
PMID: 24056174
Streptavidin is one of the most important hubs for molecular biology, either multimerizing biomolecules, bridging one molecule to another, or anchoring to a biotinylated surface/nanoparticle. Streptavidin has the advantage of...
23.
Ren Q, Henes B, Fairhead M, Thony-Meyer L
BMC Biotechnol
. 2013 Feb;
13:18.
PMID: 23442796
Background: Tyrosinase is a bifunctional enzyme that catalyzes both the hydroxylation of monophenols to o-diphenols (monophenolase activity) and the subsequent oxidation of the diphenols to o-quinones (diphenolase activity). Due to...
24.
Fairhead M, Thony-Meyer L
N Biotechnol
. 2011 Jun;
29(2):183-91.
PMID: 21664502
Tyrosinases are copper-containing dioxygen activating enzymes found in many species of bacteria and are usually associated with melanin production. These proteins have a strong preference for phenolic and diphenolic substrates...
25.
Bischof D, Hardmeier S, Fairhead M, Ihssen J, Thony-Meyer L
Anal Biochem
. 2010 Oct;
409(2):213-9.
PMID: 20971052
Detection methods for immunoblot analysis are often based on peroxidase conjugates. However, molecular weight markers directly detectable for general use in such systems are not available. Here, we describe the...
26.
Fairhead M, Thony-Meyer L
J Biotechnol
. 2010 Oct;
150(4):546-51.
PMID: 20969899
This paper reports on the cross-linking and immobilisation of various proteins by the recombinant tyrosinase from Verrucomicrobium spinosum (Vs-tyrosinase). In general it is found that Vs-tyrosinase can readily cross-link proteins...
27.
Fairhead M, Thony-Meyer L
FEBS J
. 2010 Mar;
277(9):2083-95.
PMID: 20345903
The well studied bacterial tyrosinases from the Streptomyces sp. bacteria are distinguishable from their eukaryotic counterparts by the absence of a C-terminal extension. In the present study, we report that...
28.
Fairhead M, Johnson K, Kowatz T, McMahon S, Carter L, Oke M, et al.
Chem Commun (Camb)
. 2008 Apr;
(15):1765-7.
PMID: 18379686
Cathepsin L mutants with the ability to condense silica from solution have been generated and a 1.5 A crystal structure of one of these chimeras allows us to rationalise the...
29.
Fairhead M, van der Walle C
Protein Pept Lett
. 2008 Jan;
15(1):47-53.
PMID: 18221013
Differences evident in the sequence alignment of human cathepsin-L with shrimp cathepsin-L and silicatein-alpha suggest the indirect involvement of the heavy to light chain loop (E 286 to E 289)...
30.
Fairhead M, Kelly S, van der Walle C
Biochem Biophys Res Commun
. 2007 Dec;
366(3):862-7.
PMID: 18086562
The molecular mechanism by which heparin modulates the processing of procathepsin L in the extracellular environment is proposed. We show that heparin reduces the stability of the pro form of...