Michael E Burczynski
Overview
Explore the profile of Michael E Burczynski including associated specialties, affiliations and a list of published articles.
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29
Citations
1170
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Recent Articles
1.
Su Q, Kim S, Adewale F, Zhou Y, Aldler C, Ni M, et al.
iScience
. 2025 Feb;
28(2):111951.
PMID: 39995867
[This corrects the article DOI: 10.1016/j.isci.2021.103233.].
2.
Dunn M, Kithcart A, Kim J, Ho A, Franklin M, Romero Hernandez A, et al.
Nature
. 2024 Sep;
633(8030):654-661.
PMID: 39261724
Heart failure is a leading cause of morbidity and mortality. Elevated intracardiac pressures and myocyte stretch in heart failure trigger the release of counter-regulatory natriuretic peptides, which act through their...
3.
Zhou Y, Zhao Y, Carbonaro M, Chen H, Germino M, Adler C, et al.
Metabolism
. 2024 Mar;
154:155830.
PMID: 38428673
Liver zonation characterizes the separation of metabolic pathways along the lobules and is required for optimal hepatic function. Wnt signaling is a master regulator of spatial liver zonation. A perivenous-periportal...
4.
Mao X, Chen H, Lin A, Kim S, Burczynski M, Na E, et al.
J Inherit Metab Dis
. 2022 Jan;
45(3):470-480.
PMID: 34988999
Amino acids, the building blocks of proteins in the cells and tissues, are of fundamental importance for cell survival, maintenance, and proliferation. The liver plays a critical role in amino...
5.
Su Q, Kim S, Adewale F, Zhou Y, Aldler C, Ni M, et al.
iScience
. 2021 Nov;
24(11):103233.
PMID: 34755088
Nonalcoholic fatty liver disease (NAFLD) is a global health-care problem with limited therapeutic options. To obtain a cellular resolution of pathogenesis, 82,168 single-cell transcriptomes (scRNA-seq) across different NAFLD stages were...
6.
Davis K, Aghaeepour N, Ahn A, Angst M, Borsook D, Brenton A, et al.
Nat Rev Neurol
. 2020 Jun;
16(7):381-400.
PMID: 32541893
Pain medication plays an important role in the treatment of acute and chronic pain conditions, but some drugs, opioids in particular, have been overprescribed or prescribed without adequate safeguards, leading...
7.
Kusko R, Dreymann J, Ross J, Cha Y, Escalante-Chong R, Garcia-Miralles M, et al.
Mol Neurodegener
. 2018 May;
13(1):25.
PMID: 29783994
Background: Huntington Disease (HD) is an incurable autosomal dominant neurodegenerative disorder driven by an expansion repeat giving rise to the mutant huntingtin protein (mHtt), which is known to disrupt a...
8.
Burczynski M
Expert Opin Med Diagn
. 2013 Mar;
1(1):147-50.
PMID: 23489278
With the proliferation of high-content profiling technologies available for analyzing genetic, transcriptomic, proteomic and metabolomic markers in tissues, both novel analytes and increasingly complex signatures are emerging as biomarkers supporting...
9.
Allantaz F, Cheng D, Bergauer T, Ravindran P, Rossier M, Ebeling M, et al.
PLoS One
. 2012 Jan;
7(1):e29979.
PMID: 22276136
Blood consists of different cell populations with distinct functions and correspondingly, distinct gene expression profiles. In this study, global miRNA expression profiling was performed across a panel of nine human...
10.
Pant S, Hilton H, Burczynski M
Biochem Pharmacol
. 2012 Jan;
83(11):1484-94.
PMID: 22230477
Exosomes are bioactive vesicles derived from the cell's endosomal membrane system and secreted into surrounding body fluids. Exosomes contain cell and cell-state specific cargos of protein, mRNA and miRNA. Exosome...