Michael Del Tatto
Overview
Explore the profile of Michael Del Tatto including associated specialties, affiliations and a list of published articles.
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14
Citations
355
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Recent Articles
1.
Goldberg L, Dooner M, Papa E, Pereira M, Del Tatto M, Cheng Y, et al.
Stem Cell Rev Rep
. 2022 May;
18(7):2351-2364.
PMID: 35503199
Hematopoietic stem cells express differentiation markers B220 and Gr1 and are proliferative. We have shown that the expression of these entities changes with cell cycle passage. Overall, we conclude that...
2.
Jeong E, Pereira M, So E, Wu K, Del Tatto M, Wen S, et al.
Cardiovasc Res
. 2022 Jan;
118(16):3211-3224.
PMID: 35018410
Aims: Pulmonary arterial hypertension (PAH) is a fatal disease without a cure. Previously, we found that transcription factor RUNX1-dependent haematopoietic transformation of endothelial progenitor cells may contribute to the pathogenesis...
3.
Klinger J, Pereira M, Del Tatto M, Dooner M, Wen S, Quesenberry P, et al.
Pulm Circ
. 2022 Jan;
11(4):20458940211046137.
PMID: 34987768
Rationale: Mesenchymal stem cell extracellular vesicles (MSC EVs) reverse pulmonary hypertension, but little information is available regarding what dose is effective and how often it needs to be given. This...
4.
Klinger J, Pereira M, Del Tatto M, Brodsky A, Wu K, Dooner M, et al.
Am J Respir Cell Mol Biol
. 2019 Nov;
62(5):577-587.
PMID: 31721618
Mesenchymal stem cell extracellular vesicles attenuate pulmonary hypertension, but their ability to reverse established disease in larger animal models and the duration and mechanism(s) of their effect are unknown. We...
5.
Wen S, Dooner M, Papa E, Del Tatto M, Pereira M, Borgovan T, et al.
Int J Mol Sci
. 2019 Nov;
20(21).
PMID: 31684046
We have previously shown that injury induced by irradiation to murine marrow can be partially or completely reversed by exposure to human or murine mesenchymal stem cell (MSC)-derived extracellular vesicles...
6.
Dooner M, Stewart C, Deng Y, Papa E, Pereira M, Del Tatto M, et al.
PLoS One
. 2018 Nov;
13(11):e0207444.
PMID: 30475846
Extracellular vesicles (EVs) are important mediators of intercellular communication and have been implicated in myriad physiologic and pathologic processes within the hematopoietic system. Numerous factors influence the ability of EVs...
7.
Aliotta J, Pereira M, Wen S, Dooner M, Del Tatto M, Papa E, et al.
Stem Cells Transl Med
. 2017 May;
6(7):1595-1606.
PMID: 28474513
The role of bone marrow (BM) cells in modulating pulmonary hypertensive responses is not well understood. Determine if BM-derived endothelial progenitor cells (EPCs) induce pulmonary hypertension (PH) and if this...
8.
Aliotta J, Pereira M, Wen S, Dooner M, Del Tatto M, Papa E, et al.
Cardiovasc Res
. 2016 Mar;
110(3):319-30.
PMID: 26980205
Aims: Extracellular vesicles (EVs) from mice with monocrotaline (MCT)-induced pulmonary hypertension (PH) induce PH in healthy mice, and the exosomes (EXO) fraction of EVs from mesenchymal stem cells (MSCs) can...
9.
Mulvey H, Chang A, Adler J, Del Tatto M, Perez K, Quesenberry P, et al.
BMC Cancer
. 2015 Aug;
15:571.
PMID: 26231887
Background: Extracellular vesicles (EVs) are secreted from many cells, carrying cargoes including proteins and nucleic acids. Research has shown that EVs play a role in a variety of biological processes...
10.
Panagopoulos K, Cross-Knorr S, Dillard C, Pantazatos D, Del Tatto M, Mills D, et al.
Mol Cancer
. 2013 Oct;
12(1):118.
PMID: 24103426
Background: Extracellular vesicle (EV) trafficking is a fundamental cellular process that occurs in cells and is required for different aspects of pathophysiology. EV trafficking leads to changes in cellular function...