Mark S Dooner
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Explore the profile of Mark S Dooner including associated specialties, affiliations and a list of published articles.
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40
Citations
911
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Recent Articles
1.
Quesenberry P, Wen S, Goldberg L, Dooner M
Leukemia
. 2022 Oct;
36(12):2784-2792.
PMID: 36307485
Current dogma is that there exists a hematopoietic pluripotent stem cell, resident in the marrow, which is quiescent, but with tremendous proliferative and differentiative potential. Furthermore, the hematopoietic system is...
2.
Goldberg L, Dooner M, Papa E, Pereira M, Del Tatto M, Cheng Y, et al.
Stem Cell Rev Rep
. 2022 May;
18(7):2351-2364.
PMID: 35503199
Hematopoietic stem cells express differentiation markers B220 and Gr1 and are proliferative. We have shown that the expression of these entities changes with cell cycle passage. Overall, we conclude that...
3.
Jeong E, Pereira M, So E, Wu K, Del Tatto M, Wen S, et al.
Cardiovasc Res
. 2022 Jan;
118(16):3211-3224.
PMID: 35018410
Aims: Pulmonary arterial hypertension (PAH) is a fatal disease without a cure. Previously, we found that transcription factor RUNX1-dependent haematopoietic transformation of endothelial progenitor cells may contribute to the pathogenesis...
4.
Klinger J, Pereira M, Del Tatto M, Dooner M, Wen S, Quesenberry P, et al.
Pulm Circ
. 2022 Jan;
11(4):20458940211046137.
PMID: 34987768
Rationale: Mesenchymal stem cell extracellular vesicles (MSC EVs) reverse pulmonary hypertension, but little information is available regarding what dose is effective and how often it needs to be given. This...
5.
Klinger J, Pereira M, Del Tatto M, Brodsky A, Wu K, Dooner M, et al.
Am J Respir Cell Mol Biol
. 2019 Nov;
62(5):577-587.
PMID: 31721618
Mesenchymal stem cell extracellular vesicles attenuate pulmonary hypertension, but their ability to reverse established disease in larger animal models and the duration and mechanism(s) of their effect are unknown. We...
6.
Dooner M, Stewart C, Deng Y, Papa E, Pereira M, Del Tatto M, et al.
PLoS One
. 2018 Nov;
13(11):e0207444.
PMID: 30475846
Extracellular vesicles (EVs) are important mediators of intercellular communication and have been implicated in myriad physiologic and pathologic processes within the hematopoietic system. Numerous factors influence the ability of EVs...
7.
Zuo C, Wang L, Kamalesh R, Bowen M, Moore D, Dooner M, et al.
Bone Res
. 2018 Apr;
6:12.
PMID: 29644115
Chondrocytes and osteoblasts differentiate from a common mesenchymal precursor, the osteochondroprogenitor (OCP), and help build the vertebrate skeleton. The signaling pathways that control lineage commitment for OCPs are incompletely understood....
8.
Aliotta J, Pereira M, Wen S, Dooner M, Del Tatto M, Papa E, et al.
Stem Cells Transl Med
. 2017 May;
6(7):1595-1606.
PMID: 28474513
The role of bone marrow (BM) cells in modulating pulmonary hypertensive responses is not well understood. Determine if BM-derived endothelial progenitor cells (EPCs) induce pulmonary hypertension (PH) and if this...
9.
Li M, Tucker L, Asara J, Cheruiyot C, Lu H, Wu Z, et al.
J Clin Invest
. 2016 Jul;
126(8):3117-29.
PMID: 27454292
A rare subset of HIV-1-infected individuals is able to maintain plasma viral load (VL) at low levels without antiretroviral treatment. Identifying the mechanisms underlying this atypical response to infection may...
10.
Aliotta J, Pereira M, Wen S, Dooner M, Del Tatto M, Papa E, et al.
Cardiovasc Res
. 2016 Mar;
110(3):319-30.
PMID: 26980205
Aims: Extracellular vesicles (EVs) from mice with monocrotaline (MCT)-induced pulmonary hypertension (PH) induce PH in healthy mice, and the exosomes (EXO) fraction of EVs from mesenchymal stem cells (MSCs) can...