Michael D Gunn
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Explore the profile of Michael D Gunn including associated specialties, affiliations and a list of published articles.
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55
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3373
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Recent Articles
1.
Brown M, DAnniballe V, Boczkowski D, Kandadi H, Sheikh N, Kornahrens Jr W, et al.
Cancer Res Commun
. 2024 Sep;
4(10):2724-2733.
PMID: 39320053
Significance: The identification of factors that determine successful cancer immunotherapy, particularly in refractory tumor types like mCRPC, is urgently needed: both to identify patients that may benefit from such therapies...
2.
Tighe R, Birukova A, Malakhau Y, Kobayashi Y, Vose A, Chandramohan V, et al.
Front Immunol
. 2024 Jul;
15:1371764.
PMID: 38983858
Introduction: Environmental exposures and experimental manipulations can alter the ontogenetic composition of tissue-resident macrophages. However, the impact of these alterations on subsequent immune responses, particularly in allergic airway diseases, remains...
3.
Achanta S, Gentile M, Albert C, Schulte K, Pantazides B, Crow B, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Feb;
326(4):L482-L495.
PMID: 38318664
Chlorine gas (Cl) has been repeatedly used as a chemical weapon, first in World War I and most recently in Syria. Life-threatening Cl exposures frequently occur in domestic and occupational...
4.
DAnniballe V, Huang M, Lueck B, Nicholson L, McFatridge I, Gunn M
J Immunother
. 2023 Sep;
46(9):333-340.
PMID: 37737688
Undifferentiated monocytes can be loaded with tumor antigens (Ag) and administered intravenously to induce antitumor cytotoxic T lymphocyte (CTL) responses. This vaccination strategy exploits an endogenous Ag cross-presentation pathway, where...
5.
Lerner E, Woroniecka K, DAnniballe V, Wilkinson D, Mohan A, Lorrey S, et al.
Nat Cancer
. 2023 Aug;
4(9):1258-1272.
PMID: 37537301
The accepted paradigm for both cellular and anti-tumor immunity relies upon tumor cell killing by CD8 T cells recognizing cognate antigens presented in the context of target cell major histocompatibility...
6.
Tighe R, Birukova A, Malakhau Y, Kobayashi Y, Vose A, Chandramohan V, et al.
bioRxiv
. 2023 Feb;
PMID: 36824904
The ontogenetic composition of tissue-resident macrophages following injury, environmental exposure, or experimental depletion can be altered upon re-establishment of homeostasis. However, the impact of altered resident macrophage ontogenetic milieu on...
7.
Tomaszewski W, Waibl-Polania J, Chakraborty M, Perera J, Ratiu J, Miggelbrink A, et al.
Nat Commun
. 2022 Oct;
13(1):6483.
PMID: 36309495
Glioblastoma (GBM) is notorious for its immunosuppressive tumor microenvironment (TME) and is refractory to immune checkpoint blockade (ICB). Here, we identify calmodulin-dependent kinase kinase 2 (CaMKK2) as a driver of...
8.
Lessons from the pandemic: Responding to emerging zoonotic viral diseases-a Keystone Symposia report
Cable J, Fauci A, Dowling W, Gunther S, Bente D, Yadav P, et al.
Ann N Y Acad Sci
. 2022 Oct;
1518(1):209-225.
PMID: 36183296
The COVID-19 pandemic caught the world largely unprepared, including scientific and policy communities. On April 10-13, 2022, researchers across academia, industry, government, and nonprofit organizations met at the Keystone symposium...
9.
Shahid R, Vigna S, Huang M, Gunn M, Liddle R
Am J Physiol Gastrointest Liver Physiol
. 2022 Sep;
323(5):G420-G427.
PMID: 36126221
It has previously been shown that current smoking is protective against endoscopic retrograde cholangiopancreatography (ERCP)-induced acute pancreatitis, but the mechanism of this effect was not identified. We tested the hypothesis...
10.
Huang M, DAnniballe V, Gunn M
Methods Mol Biol
. 2021 Dec;
2410:627-647.
PMID: 34914073
We recently developed a monocyte-based cellular vaccine platform for cancer treatment. In contrast to the traditional utilization of monocytes as precursors to generate dendritic cells (DC) for vaccination purposes, we...