Michael Borja
Overview
Explore the profile of Michael Borja including associated specialties, affiliations and a list of published articles.
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6
Citations
82
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Recent Articles
1.
Zheng W, Borja M, Dorman L, Liu J, Zhou A, Seng A, et al.
Sci Adv
. 2025 Jan;
11(3):eadq8158.
PMID: 39813329
(MTB) ESX-1, a type VII secretion system, is a key virulence determinant contributing to MTB's survival within lung mononuclear phagocytes (MNPs), but its effect on MNP recruitment and differentiation remains...
2.
Lange M, Granados A, VijayKumar S, Bragantini J, Ancheta S, Kim Y, et al.
Cell
. 2024 Oct;
187(23):6742-6759.e17.
PMID: 39454574
Elucidating organismal developmental processes requires a comprehensive understanding of cellular lineages in the spatial, temporal, and molecular domains. In this study, we introduce Zebrahub, a dynamic atlas of zebrafish embryonic...
3.
VijayKumar S, Borja M, Neff N, Royer L, Lange M
MethodsX
. 2024 Sep;
13:102958.
PMID: 39329153
Single-cell sequencing has revolutionized our understanding of cellular heterogeneity and cell state, enabling investigations across diverse fields such as developmental biology, immunology, and cancer biology. However, obtaining a high-quality single-cell...
4.
Winkler J, Tan W, Diadhiou C, McGinnis C, Abbasi A, Hasnain S, et al.
J Clin Invest
. 2024 Sep;
134(17).
PMID: 39225101
Metastasis is the leading cause of cancer-related deaths. It is unclear how intratumor heterogeneity (ITH) contributes to metastasis and how metastatic cells adapt to distant tissue environments. The study of...
5.
Zheng W, Borja M, Dorman L, Liu J, Zhou A, Seng A, et al.
bioRxiv
. 2024 May;
PMID: 38712150
Mycobacterium tuberculosis (MTB) infects and replicates in lung mononuclear phagocytes (MNPs) with astounding ability to evade elimination. ESX-1, a type VII secretion system, acts as a virulence determinant that contributes...
6.
Liu J, Tran V, Vemuri V, Byrne A, Borja M, Kim Y, et al.
Life Sci Alliance
. 2022 Dec;
6(1).
PMID: 36526371
Spatial transcriptomics extends single-cell RNA sequencing (scRNA-seq) by providing spatial context for cell type identification and analysis. Imaging-based spatial technologies such as multiplexed error-robust fluorescence in situ hybridization (MERFISH) can...
7.
Palovics R, Keller A, Schaum N, Tan W, Fehlmann T, Borja M, et al.
Nature
. 2022 Mar;
603(7900):309-314.
PMID: 35236985
The ability to slow or reverse biological ageing would have major implications for mitigating disease risk and maintaining vitality. Although an increasing number of interventions show promise for rejuvenation, their...