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Michael B A Oldstone

Explore the profile of Michael B A Oldstone including associated specialties, affiliations and a list of published articles. Areas
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Articles 141
Citations 7364
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Recent Articles
1.
Zak J, Pratumchai I, Marro B, Marquardt K, Zavareh R, Lairson L, et al.
Science . 2024 Jun; 384(6702):eade8520. PMID: 38900864
Unleashing antitumor T cell activity by checkpoint inhibitor immunotherapy is effective in cancer patients, but clinical responses are limited. Cytokine signaling through the Janus kinase (JAK)-signal transducer and activator of...
2.
Kotliar D, Raju S, Tabrizi S, Odia I, Goba A, Momoh M, et al.
Nat Microbiol . 2024 Feb; 9(3):751-762. PMID: 38326571
Infection with Lassa virus (LASV) can cause Lassa fever, a haemorrhagic illness with an estimated fatality rate of 29.7%, but causes no or mild symptoms in many individuals. Here, to...
3.
LaVergne S, Sakabe S, Momoh M, Kanneh L, Bond N, Garry R, et al.
PLoS Negl Trop Dis . 2022 Nov; 16(11):e0010882. PMID: 36441765
Introduction: Lassa virus is a priority pathogen for vaccine research and development, however the duration of cellular immunity and protection in Lassa fever (LF) survivors remains unclear. Methods: We investigated...
4.
Pratumchai I, Zak J, Huang Z, Min B, Oldstone M, Teijaro J
Proc Natl Acad Sci U S A . 2022 Jan; 119(3). PMID: 35022243
Recent studies have identified a critical role for B cell-produced cytokines in regulating both humoral and cellular immunity. Here, we show that B cells are an essential source of interleukin-27...
5.
Brooks D, Tishon A, Oldstone M, McGavern D
Viruses . 2021 Jul; 13(7). PMID: 34206262
During chronic viral infections, CD8 T cells rapidly lose antiviral and immune-stimulatory functions in a sustained program termed exhaustion. In addition to this loss of function, CD8 T cells with...
6.
Oldstone M, Ware B, Davidson A, Prescott M, Beynon R, Hurst J
Viruses . 2021 Jul; 13(6). PMID: 34205512
Mature male mice produce a particularly high concentration of major urinary proteins (MUPs) in their scent marks that provide identity and status information to conspecifics. Darcin (MUP20) is inherently attractive...
7.
Rosen H, Oldstone M
EMBO Mol Med . 2020 Dec; 13(1):e13533. PMID: 33326687
The sphingosine-1-phosphate (S1P) is a lysophospholipid signaling molecule with important functions in many physiological and pathological conditions, including viral infection. In this issue of EMBO Molecular Medicine, Marfia et al...
8.
LaVergne S, Sakabe S, Kanneh L, Momoh M, Al-Hassan F, Yilah M, et al.
J Infect Dis . 2020 May; 222(9):1488-1497. PMID: 32436943
Background: Ebola virus (EBOV) disease has killed thousands of West and Central Africans over the past several decades. Many who survive the acute disease later experience post-Ebola syndrome, a constellation...
9.
Sakabe S, Hartnett J, Ngo N, Goba A, Momoh M, Sandi J, et al.
J Virol . 2020 Apr; 94(12). PMID: 32269122
Early and robust T cell responses have been associated with survival from Lassa fever (LF), but the Lassa virus-specific memory responses have not been well characterized. Regions within the virus...
10.
Oldstone M, Lampert P
Springer Semin Immunopathol . 2020 Mar; 2(3):261-283. PMID: 32214619
No abstract available.