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Michael Atchison

Explore the profile of Michael Atchison including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 264
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Recent Articles
1.
Syrett C, Paneru B, Sandoval-Heglund D, Wang J, Banerjee S, Sindhava V, et al.
JCI Insight . 2019 Apr; 4(7). PMID: 30944248
Systemic lupus erythematosus (SLE) is an autoimmune disorder that predominantly affects women and is driven by autoreactive T cell-mediated inflammation. It is known that individuals with multiple X-chromosomes are at...
2.
Syrett C, Sindhava V, Sierra I, Dubin A, Atchison M, Anguera M
Front Immunol . 2019 Jan; 9:3087. PMID: 30671059
In females, the long non-coding RNA Xist drives X-chromosome Inactivation (XCI) to equalize X-linked gene dosage between sexes. Unlike other somatic cells, dynamic regulation of Xist RNA and heterochromatin marks...
3.
Syrett C, Sindhava V, Hodawadekar S, Myles A, Liang G, Zhang Y, et al.
PLoS Genet . 2017 Oct; 13(10):e1007050. PMID: 28991910
X-chromosome inactivation (XCI) in female lymphocytes is uniquely regulated, as the inactive X (Xi) chromosome lacks localized Xist RNA and heterochromatin modifications. Epigenetic profiling reveals that Xist RNA is lost...
4.
Atchison M, Basu A, Zaprazna K, Papasani M
Crit Rev Oncog . 2012 Jan; 16(3-4):143-61. PMID: 22248052
Yin Yang 1 (YY1) is a ubiquitously expressed transcription factor that performs numerous functions including transcriptional regulation, cell growth control, apoptosis, large-scale chromosomal dynamics, and X-chromosome inactivation. YY1 clearly is...
5.
Azim A, Wang X, Park G, Sadikot R, Cao H, Mathew B, et al.
J Immunol . 2007 Nov; 179(11):7868-75. PMID: 18025233
Selective expression of cyclooxygenase 2 (COX-2) by macrophages could have an important role in the pathobiology of inflammation. We reported a functional synergism between PU.1 and other transcription factors that...
6.
Calame K, Atchison M
Genes Dev . 2007 May; 21(10):1145-52. PMID: 17504933
No abstract available.
7.
Atchison M
J Vet Med Educ . 2005 Nov; 32(3):337-41. PMID: 16261494
The Veterinary Medical Scientist Training Program (VMSTP), a combined degree program at the University of Pennsylvania School of Veterinary Medicine (Penn), has been in existence for approximately 35 years and...
8.
Boopathi E, Lenka N, Prabu S, Fang J, Wilkinson F, Atchison M, et al.
J Biol Chem . 2004 Jun; 279(34):35242-54. PMID: 15190078
A transcription suppressor element (sequence -481 to -320) containing a G-rich motif (designated GTG) and a newly identified CAT-rich motif (designated CATR) was previously shown to modulate expression of the...
9.
Hong W, Kim A, Ky S, Rakowski C, Seo S, Chakravarti D, et al.
Mol Cell Biol . 2002 May; 22(11):3729-43. PMID: 11997509
Aberrant expression of PU.1 inhibits erythroid cell differentiation and contributes to the formation of murine erythroleukemias (MEL). The molecular mechanism by which this occurs is poorly understood. Here we show...