Michael A Prakesch
Overview
Explore the profile of Michael A Prakesch including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
11
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Recent Articles
1.
Chandler F, Reddy P, Bhutda S, Ross R, Datta A, Walden M, et al.
bioRxiv
. 2024 Sep;
PMID: 39282282
Deubiquitylases (DUBs) are crucial in cell signalling and are often regulated by interactions within protein complexes. The BRCC36 isopeptidase complex (BRISC) regulates inflammatory signalling by cleaving K63-linked polyubiquitin chains on...
2.
Mamai A, Chau A, Wilson B, Watson I, Joseph B, Subramanian P, et al.
ACS Med Chem Lett
. 2023 Feb;
14(2):199-210.
PMID: 36793435
B cell lymphoma 6 (BCL6), a highly regulated transcriptional repressor, is deregulated in several forms of non-Hodgkin lymphoma (NHL), most notably in diffuse large B-cell lymphoma (DLBCL). The activities of...
3.
Uehling D, Joseph B, Chung K, Zhang A, Ler S, Prakesch M, et al.
J Med Chem
. 2021 Dec;
65(1):886-887.
PMID: 34963044
No abstract available.
4.
Uehling D, Joseph B, Chung K, Zhang A, Ler S, Prakesch M, et al.
J Med Chem
. 2021 Jul;
64(15):11129-11147.
PMID: 34291633
Both previous and additional genetic knockdown studies reported herein implicate G protein-coupled receptor kinase 6 (GRK6) as a critical kinase required for the survival of multiple myeloma (MM) cells. Therefore,...