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Michael A Chesney

Explore the profile of Michael A Chesney including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 218
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Recent Articles
1.
Evans K, Huang N, Stempor P, Chesney M, Down T, Ahringer J
Proc Natl Acad Sci U S A . 2016 Oct; 113(45):E7020-E7029. PMID: 27791097
Eukaryotic genomes are organized into domains of differing structure and activity. There is evidence that the domain organization of the genome regulates its activity, yet our understanding of domain properties...
2.
Latorre I, Chesney M, Garrigues J, Stempor P, Appert A, Francesconi M, et al.
Genes Dev . 2015 Mar; 29(5):495-500. PMID: 25737279
The DREAM (DP, Retinoblastoma [Rb]-like, E2F, and MuvB) complex controls cellular quiescence by repressing cell cycle genes, but its mechanism of action is poorly understood. Here we show that Caenorhabditis...
3.
Chesney M, Lam N, Morgan D, Phillips B, Kimble J
Dev Biol . 2009 Apr; 331(1):14-25. PMID: 19376107
The Caenorhabditis elegans distal tip cell (DTC) provides a niche for germline stem cells in both hermaphrodites and males. The hermaphrodite distal tip cell (hDTC) also provides "leader" function to...
4.
Lam N, Chesney M, Kimble J
Curr Biol . 2006 Feb; 16(3):287-95. PMID: 16461282
Wnt signaling regulates many aspects of metazoan development, including stem cells. In C. elegans, Wnt/MAPK signaling controls asymmetric divisions. A recent model proposed that the POP-1/TCF DNA binding protein works...
5.
Chesney M, Kidd 3rd A, Kimble J
Genetics . 2005 Dec; 172(2):915-28. PMID: 16322520
Previous work showed that C. elegans gon-14 is required for gonadogenesis. Here we report that gon-14 encodes a protein with similarity to LIN-15B, a class B synMuv protein. An extensive...
6.
Siegfried K, Kidd 3rd A, Chesney M, Kimble J
Genetics . 2004 Mar; 166(1):171-86. PMID: 15020416
To form the proximal-distal axis of the C. elegans gonad, two somatic gonadal precursor cells, Z1 and Z4, divide asymmetrically to generate one daughter with a proximal fate and one...
7.
Chesney M, Perouansky M, Pearce R
Anesthesiology . 2003 Jun; 99(1):122-30. PMID: 12826851
Background: The rate of onset of drug actions in experiments with brain slices in vitro can vary widely. One factor that influences the rate is access to tissue sites of...