Michael A Black
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Explore the profile of Michael A Black including associated specialties, affiliations and a list of published articles.
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101
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2839
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Recent Articles
1.
Bilton T, Sharma S, Schofield M, Black M, Jacobs J, Bryan G, et al.
Theor Appl Genet
. 2024 Mar;
137(3):64.
PMID: 38430392
An improved estimator of genomic relatedness using low-depth high-throughput sequencing data for autopolyploids is developed. Its outputs strongly correlate with SNP array-based estimates and are available in the package GUSrelate....
2.
Maurin M, Ranjouri M, Megino-Luque C, Newberg J, Du D, Martin K, et al.
Nat Commun
. 2023 Dec;
14(1):8444.
PMID: 38114498
RNA splicing is an important biological process associated with cancer initiation and progression. However, the contribution of alternative splicing to pancreatic cancer (PDAC) development is not well understood. Here, we...
3.
McGuinness C, Black M, Dunbier A
Cancer Med
. 2023 Nov;
12(23):21545-21560.
PMID: 37974533
Background: Genome-wide measures of genetic disruption such as tumour mutation burden (TMB) and mutation signatures are emerging as useful biomarkers to stratify patients for treatment. Clinicians commonly use cancer gene...
4.
Te Aika B, Liggins L, Rye C, Perkins E, Huh J, Brauning R, et al.
Mol Ecol Resour
. 2023 Sep;
25(2):e13866.
PMID: 37712601
The Aotearoa Genomic Data Repository (AGDR) is an initiative to provide a secure within-nation option for the storage, management and sharing of non-human genomic data generated from biological and environmental...
5.
Yang Z, Guarracino A, Biggs P, Black M, Ismail N, Wold J, et al.
Front Genet
. 2023 Aug;
14:1225248.
PMID: 37636268
Whole genome sequencing has revolutionized infectious disease surveillance for tracking and monitoring the spread and evolution of pathogens. However, using a linear reference genome for genomic analyses may introduce biases,...
6.
Taylor M, Black M, Hampton M, Ledgerwood E
Free Radic Res
. 2023 Jan;
56(9-10):666-676.
PMID: 36630571
Hydrogen peroxide (HO) is a ubiquitous oxidant produced in a regulated manner by various enzymes in mammalian cells. HO reversibly oxidizes thiol groups of cysteine residues to mediate intracellular signaling....
7.
Mehta S, Wright D, Black M, Merrie A, Anjomshoaa A, Munro F, et al.
JNCI Cancer Spectr
. 2022 Oct;
6(6).
PMID: 36255250
Genomic analysis of tumors is transforming our understanding of cancer. However, although a great deal of attention is paid to the accuracy of the cancer genomic data itself, less attention...
8.
Bougen-Zhukov N, Decourtye-Espiard L, Mitchell W, Redpath K, Perkinson J, Godwin T, et al.
Cancers (Basel)
. 2022 Apr;
14(7).
PMID: 35406381
The gene, encoding the cell adhesion protein E-cadherin, is one of the most frequently mutated genes in gastric cancer and inactivating germline mutations are responsible for the cancer syndrome hereditary...
9.
Gardner P, Paterson J, McGimpsey S, Ashari-Ghomi F, Umu S, Pawlik A, et al.
Genome Biol
. 2022 Feb;
23(1):56.
PMID: 35172880
Background: Computational biology provides software tools for testing and making inferences about biological data. In the face of increasing volumes of data, heuristic methods that trade software speed for accuracy...
10.
Decourtye-Espiard L, Bougen-Zhukov N, Godwin T, Brew T, Schulpen E, Black M, et al.
Cancers (Basel)
. 2022 Jan;
14(1).
PMID: 35008338
Inactivating germline mutations in the gene (encoding the E-cadherin protein) are the genetic hallmark of hereditary diffuse gastric cancer (HDGC), and somatic mutations are an early event in the development...