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Justin Y Newberg

Explore the profile of Justin Y Newberg including associated specialties, affiliations and a list of published articles. Areas
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Articles 36
Citations 686
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Recent Articles
1.
Maurin M, Ranjouri M, Megino-Luque C, Newberg J, Du D, Martin K, et al.
Nat Commun . 2023 Dec; 14(1):8444. PMID: 38114498
RNA splicing is an important biological process associated with cancer initiation and progression. However, the contribution of alternative splicing to pancreatic cancer (PDAC) development is not well understood. Here, we...
2.
Serebriiskii I, Pavlov V, Andrianov G, Litwin S, Basickes S, Newberg J, et al.
NPJ Genom Med . 2023 Nov; 8(1):40. PMID: 38001126
Somatic PTEN mutations are common and have driver function in some cancer types. However, in colorectal cancers (CRCs), somatic PTEN-inactivating mutations occur at a low frequency (~8-9%), and whether these...
3.
Jiagge E, Jin D, Newberg J, Perea-Chamblee T, Pekala K, Fong C, et al.
Cancer Cell . 2023 Oct; 41(11):1963-1971.e3. PMID: 37890492
Cancer genomes from patients with African (AFR) ancestry have been poorly studied in clinical research. We leverage two large genomic cohorts to investigate the relationship between genomic alterations and AFR...
4.
Moore J, Chen K, Madison R, Newberg J, Fleischmann Z, Wang S, et al.
JCO Precis Oncol . 2023 Sep; 7:e2300093. PMID: 37769224
Purpose: Copy-number (CN) features reveal the molecular state of cancers and may have predictive and prognostic value in the treatment of cancer. We sought to apply published CN analysis methods...
5.
Sivakumar S, Lee J, Moore J, Hopkins J, Newberg J, Madison R, et al.
Lancet Digit Health . 2023 May; 5(6):e380-e389. PMID: 37236698
Background: Men of African ancestry experience the greatest burden of prostate cancer globally, but they are under-represented in genomic and precision medicine studies. Therefore, we sought to characterise the genomic...
6.
Sivakumar S, Moore J, Montesion M, Sharaf R, Lin D, Colon C, et al.
Cancer Discov . 2023 Apr; 13(7):1572-1591. PMID: 37062002
Significance: Minimal changes in therapy and survival outcomes have occurred in SCLC for the past four decades. The identification of new genetic subtypes and novel recurrent mutations as well as...
7.
Chen J, Murugesan K, Newberg J, Sokol E, Savage H, Stout T, et al.
JCO Precis Oncol . 2022 Nov; 6:e2200341. PMID: 36446041
Purpose: Understanding the differences in biomarker prevalence that may exist among diverse populations is invaluable to accurately forecast biomarker-driven clinical trial enrollment metrics and to advance inclusive research and health...
8.
Vaishnavi A, Juan J, Jacob M, Stehn C, Gardner E, Scherzer M, et al.
Cancer Res . 2022 Sep; 82(22):4261-4273. PMID: 36112789
Significance: Loss of RBMS3 cooperates with BRAFV600E to induce lung tumorigenesis, providing a deeper understanding of the molecular mechanisms underlying mutant BRAF-driven lung cancer and potential strategies to more effectively...
9.
Myer P, Lee J, Madison R, Pradhan K, Newberg J, Isasi C, et al.
Cancer Discov . 2022 Feb; 12(5):1282-1293. PMID: 35176763
Significance: KRAS (particularly KRASG12D/G13), APC, and PIK3CA were more frequently altered in AFR who had a lower frequency of MSI-H tumors. There were no differences in actionable kinase driver alterations....
10.
Lai J, Reddy A, Newberg J, Montesion M, Chang P
JCO Precis Oncol . 2022 Feb; 3:1-5. PMID: 35100713
No abstract available.